• Immunofluorescence analysis of HeLa cells using Actinin-Alpha 2 monoclonal antibody.
  • Western blot analysis using Actinin-Alpha 2 monoclonal antibody against HepG2 cell lysate.

Anti-ACTN2 antibody (C-Term) (STJ98460)

SKU:
STJ98460

Current Stock:
Host: Mouse
Applications: WB/IF
Reactivity: Human/Rat/Cow/Chicken/Dog/Pig/Zebrafish
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Alpha-actinin-2 (C-Term) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Conjugation: Unconjugated
Formulation: Liquid in 0.1M Tris-Glycine (pH7.4, 150 mM NaCl) , 0.2% Sodium Azide and 50% Glycerol.
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-1:2000
IF 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACTN2
Gene ID: 88
Uniprot ID: ACTN2_HUMAN
Immunogen Region: C-Term
Specificity: Actinin-Alpha 2 Monoclonal Antibody detects endogenous levels of Actinin-Alpha 2 protein.
Immunogen: Purified recombinant human Actinin-Alpha 2 (C-terminus) protein fragments expressed in E.coli.
Post Translational Modifications Ubiquitinated by FBXL22, leading to proteasomal degradation.
Function F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Protein Name Alpha-Actinin-2
Alpha-Actinin Skeletal Muscle Isoform 2
F-Actin Cross-Linking Protein
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-373753
Reactome: R-HSA-390522
Reactome: R-HSA-438066
Reactome: R-HSA-442982
Reactome: R-HSA-5673001
Reactome: R-HSA-9609736
Reactome: R-HSA-9617324
Reactome: R-HSA-9620244
Cellular Localisation Cytoplasm
Myofibril
Sarcomere
Z Line
Colocalizes With Myoz1 And Flnc At The Z-Lines Of Skeletal Muscle
Alternative Antibody Names Anti-Alpha-Actinin-2 antibody
Anti-Alpha-Actinin Skeletal Muscle Isoform 2 antibody
Anti-F-Actin Cross-Linking Protein antibody
Anti-ACTN2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance