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Anti-ADNP antibody

[STJ91502] Download PDF Print Data Sheet

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Product name Anti-ADNP antibody
Short Description Rabbit Polyclonal to ADNP.
Description ADNP is a protein encoded by the ADNP gene which is approximately 123,5 kDa. It is a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. It may also increase the viability of certain cell types through modulation of p53 activity. ADNP is widely expressed with strong expression in heart, skeletal muscle, kidney and placenta. Mutations in the ADNP gene may result in Helsmoortel-van der Aa syndrome. STJ91502 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ADNP protein.
Applications IHC-p, ELISA, WB
Dilution range WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
Specificity ADNP Polyclonal Antibody detects endogenous levels of ADNP protein.
Protein Name Activity-dependent neuroprotector homeobox protein
Activity-dependent neuroprotective protein
Immunogen Synthesized peptide derived from human ADNP
Immunogen Region 80-160 aa, N-terminal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 23394
Gene Symbol ADNP
Molecular Weight 124 kDa
Database Links HGNC:15766
OMIM:611386
Alternative Names ADNP antibody
ADNP1 antibody
KIAA0784 antibody
Activity-dependent neuroprotector homeobox protein antibody
Activity-dependent neuroprotective protein antibody
Function Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.
Cellular Localization Nucleus
Tissue Specificity Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissue

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