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Anti-CD164 antibody

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Anti-CD164 antibody

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Product name Anti-CD164 antibody
Description Rabbit Polyclonal to CD164.
Applications IHC-p, ELISA
Dilution range IHC 1:100-1:300
ELISA 1:20000
Specificity CD164 Polyclonal Antibody detects endogenous levels of CD164 protein.
Protein Name Sialomucin core protein 24
MUC-24
Endolyn
Multi-glycosylated core protein 24
MGC-24
MGC-24v
CD antigen CD164
Immunogen Synthesized peptide derived from human CD164
Immunogen Region 110-190 aa, C-terminal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 8763
Gene Symbol CD164
Molecular Weight 20.011 kDa
Database Links HGNC:1632
OMIM:603356
Alternative Names CD164 antibody
Sialomucin core protein 24 antibody
MUC-24 antibody
Endolyn antibody
Multi-glycosylated core protein 24 antibody
MGC-24 antibody
MGC-24v antibody
CD antigen CD164 antibody
Function Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes (By similarity).
Post-translational Modifications Highly N- and O-glycosylated; contains sialic acid. ; The motif Ser-Gly may serve as the site of attachment of a glycosaminoglycan side chain.
Cellular Localization Lysosome membrane Endosome membrane Cell membrane ; Isoform 2: Secreted
Tissue Specificity Isoform 1 and isoform 3 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseo

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Nyegaard M, Rendtorff ND, Nielsen MS, et al.. A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment. PlOS Genetics. 2015. DOI:10.1371/journal.pgen.1005386