• Immunohistochemical analysis of paraffin-embedded Human skeletal muscle. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Western blot analysis of lysates from Jurkat and HepG2 cells, using ELOVL1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using ELOVL1 Polyclonal Antibody diluted at 1：1000

Anti-ELOVL1 antibody (101-150 aa) (STJ92900)

SKU:
STJ92900

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Elongation of very long chain fatty acids protein 1 (101-150 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ELOVL1
Gene ID: 64834
Uniprot ID: ELOV1_HUMAN
Immunogen Region: 101-150 aa
Specificity: ELOVL1 Polyclonal Antibody detects endogenous levels of ELOVL1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ELOVL1 at the amino acid range 101-150
Function Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Protein Name Elongation Of Very Long Chain Fatty Acids Protein 1
3-Keto Acyl-Coa Synthase Elovl1
Elovl Fatty Acid Elongase 1
Elovl Fa Elongase 1
Very Long Chain 3-Ketoacyl-Coa Synthase 1
Very Long Chain 3-Oxoacyl-Coa Synthase 1
Database Links Reactome: R-HSA-2046105
Reactome: R-HSA-2046106
Reactome: R-HSA-75876
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Elongation Of Very Long Chain Fatty Acids Protein 1 antibody
Anti-3-Keto Acyl-Coa Synthase Elovl1 antibody
Anti-Elovl Fatty Acid Elongase 1 antibody
Anti-Elovl Fa Elongase 1 antibody
Anti-Very Long Chain 3-Ketoacyl-Coa Synthase 1 antibody
Anti-Very Long Chain 3-Oxoacyl-Coa Synthase 1 antibody
Anti-ELOVL1 antibody
Anti-SSC1 antibody
Anti-CGI-88 antibody

Information sourced from Uniprot.org

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