• Western blot analysis of extracts of various cell lines, using HTR1D antibody (STJ28077) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-HTR1D antibody (150-250) (STJ28077)

SKU:
STJ28077

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-HTR1D (150-250) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HTR1D
Gene ID: 3352
Uniprot ID: 5HT1D_HUMAN
Immunogen Region: 150-250
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human HTR1D (NP_000855.1).
Immunogen Sequence: RTAGHAATMIAIVWAISICI SIPPLFWRQAKAQEEMSDCL VNTSQISYTIYSTCGAFYIP SVLLIILYGRIYRAARNRIL NPPSLYGKRFTTAHLITGSA G
Tissue Specificity Detected in brain neocortex and caudate nucleus (at protein level).
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction.
Protein Name 5-Hydroxytryptamine Receptor 1d
5-Ht-1d
5-Ht1d
Serotonin 1d Alpha Receptor
5-Ht-1d-Alpha
Serotonin Receptor 1d
Database Links Reactome: R-HSA-390666
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-5-Hydroxytryptamine Receptor 1d antibody
Anti-5-Ht-1d antibody
Anti-5-Ht1d antibody
Anti-Serotonin 1d Alpha Receptor antibody
Anti-5-Ht-1d-Alpha antibody
Anti-Serotonin Receptor 1d antibody
Anti-HTR1D antibody
Anti-HTR1DA antibody
Anti-HTRL antibody

Information sourced from Uniprot.org

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