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Anti-IL-13Rα1 antibody

[STJ93678] Download PDF Print Data Sheet

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Product name Anti-IL-13Rα1 antibody
Description Rabbit Polyclonal to IL-13Rα1.
Applications IHC-p, ELISA, IF, WB
Dilution range WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Specificity IL-13Rα1 Polyclonal Antibody detects endogenous levels of IL-13Rα1 protein.
Protein Name Interleukin-13 receptor subunit alpha-1
IL-13 receptor subunit alpha-1
IL-13R subunit alpha-1
IL-13R-alpha-1
IL-13RA1
Cancer/testis antigen 19
CT19
CD antigen CD213a1
Immunogen Synthesized peptide derived from human IL-13Rα1 around the non-phosphorylation site of Y405.
Immunogen Region 340-420 aa
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 3597
Gene Symbol IL13RA1
Molecular Weight 49 kDa
Database Links HGNC:5974
OMIM:300119
Alternative Names IL13RA1 antibody
IL13R antibody
IL13RA antibody
Interleukin-13 receptor subunit alpha-1 antibody
IL-13 receptor subunit alpha-1 antibody
IL-13R subunit alpha-1 antibody
IL-13R-alpha-1 antibody
IL-13RA1 antibody
Cancer/testis antigen 19 antibody
CT19 antibody
CD antigen CD213a1 antibody
Function Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Cellular Localization Membrane; Single-pass type I membrane protein.
Tissue Specificity Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.
Sequence and Domain Family The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.; The box 1 motif is required for JAK interaction and/or activation.

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