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Anti-IL7R antibody

[STJ24192] Download PDF Print Data Sheet

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Product name Anti-IL7R antibody
Short Description Rabbit Polyclonal against IL7R protein
Description The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008]
Applications IF, WB
Dilution range WB 1:500-1:2000
IHC 1:50-1:200
IF 1:50-1:200
Protein Name Interleukin-7 receptor subunit alpha
IL-7 receptor subunit alpha
IL-7R subunit alpha
CD antigen CD127
Immunogen Recombinant peptide derived from human IL7R.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Concentration 1 mg/ml
Purification Anti-IL7R antibody was affinity purified using immunizing peptide
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Gene ID 3575
Gene Symbol IL7R
Database Links HGNC:6024
Alternative Names IL7R antibody
Interleukin-7 receptor subunit alpha antibody
IL-7 receptor subunit alpha antibody
IL-7R subunit alpha antibody
IL-7R-alpha antibody
IL-7RA antibody
CDw127 antibody
CD antigen CD127 antibody


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Andrea Knight,#1,2,* Pavel Nemec,1 Sona Bretzova,1,5 Lucie Valkova,1,5 Marketa Kolmanova,1,5 Renata Vytopilova,1,5 Marek Havelka,1,5 Pavla Vsianska,3 Lucie Rihova,3 Marta Krejci,4 and Martin Piskacek#1,5,* Do human B-lymphocytes avoid aging until 60 years? Oncotarget. 2016 Jul 12; 7(28): 42873–42880. Published online 2016 Jun 17. doi: 10.18632/oncotarget.10146