| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SFRP2 (25-295) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SFRP2 |
| Gene ID: |
6423 |
| Uniprot ID: |
SFRP2_HUMAN |
| Immunogen Region: |
25-295 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 25-295 of human SFRP2 (NP_003004.1). |
| Immunogen Sequence: |
LFLFGQPDFSYKRSNCKPIP ANLQLCHGIEYQNMRLPNLL GHETMKEVLEQAGAWIPLVM KQCHPDTKKFLCSLFAPVCL DDLDETIQPCHSLCVQVKDR CAPVMSAFGFPWPDMLECDR FPQDNDLCIPLASSDHLLPA TEEAPKVCEACKNKNDDDND IMETLCKNDFALKIKVKEIT YINRDTKIILETKSKTIYKL NGVSERDLKKSVLWLKDSLQ CTCEEMNDINAPYLVMGQK |
| Tissue Specificity | Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. |
| Protein Name | Secreted Frizzled-Related Protein 2Frp-2Sfrp-2Secreted Apoptosis-Related Protein 1Sarp-1 |
| Database Links | Reactome: R-HSA-201681Reactome: R-HSA-3772470 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Secreted Frizzled-Related Protein 2 antibodyAnti-Frp-2 antibodyAnti-Sfrp-2 antibodyAnti-Secreted Apoptosis-Related Protein 1 antibodyAnti-Sarp-1 antibodyAnti-SFRP2 antibodyAnti-FRP2 antibodyAnti-SARP1 antibodyAnti-FKSG12 antibodyAnti-UNQ361 antibodyAnti-PRO697 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
