| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SH3BP2 (392-561) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SH3BP2 |
| Gene ID: |
6452 |
| Uniprot ID: |
3BP2_HUMAN |
| Immunogen Region: |
392-561 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 392-561 of human SH3BP2 (NP_001116153.1). |
| Immunogen Sequence: |
VPEAMARPAVLPRPEKPQLP HLQRSPPDGQSFRSFSFEKP RQPSQADTGGDDSDEDYEKV PLPNSVFVNTTESCEVERLF KATSPRGEPQDGLYCIRNSS TKSGKVLVVWDETSNKVRNY RIFEKDSKFYLEGEVLFVSV GSMVEHYHTHVLPSHQSLLL RHPYGYTGPR |
| Tissue Specificity | Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas. |
| Post Translational Modifications | Phosphorylated. Phosphorylation at Tyr-448 may stimulate the activity of the LYN kinase. |
| Function | Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols.linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism. |
| Protein Name | Sh3 Domain-Binding Protein 23bp-2 |
| Alternative Antibody Names | Anti-Sh3 Domain-Binding Protein 2 antibodyAnti-3bp-2 antibodyAnti-SH3BP2 antibodyAnti-3BP2 antibodyAnti-RES4-23 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
