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Anti-TBPL1 antibody

[STJ29712] Download PDF Print Data Sheet

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Product name Anti-TBPL1 antibody
Short Description Rabbit Polyclonal against TBPL1 protein
Description This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
Applications IF, WB
Dilution range WB 1:500-1:2000
IHC 1:50-1:200
Protein Name TATA box-binding protein-like protein 1
TBP-like protein 1
21 kDa TBP-like protein
Second TBP of unique DNA protein
STUD
TATA box-binding protein-related factor 2
TBP-related factor 2
TBP-like factor
TBP-related protein
Immunogen Recombinant peptide derived from human TBPL1.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse
Conjugation Unconjugated
Concentration 1 mg/ml
Purification Anti-TBPL1 antibody was affinity purified using immunizing peptide
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Gene ID 9519
Gene Symbol TBPL1
Database Links HGNC:11589
OMIM:605521
Alternative Names TBPL1 antibody
TLF antibody
TLP antibody
TLP21 antibody
TRF2 antibody
TRP antibody
TATA box-binding protein-like protein 1 antibody
TBP-like protein 1 antibody
21 kDa TBP-like protein antibody
Second TBP of unique DNA protein antibody
STUD antibody
TATA box-binding protein-related factor 2 antibody
TBP-related factor 2 antibody
TBP-like factor antibody
TBP-related protein antibody
Function Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box.
Cellular Localization Cytoplasm Nucleus
Tissue Specificity Ubiquitously expressed, with highest levels in the testis and ovary.

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