• Western blot analysis of extracts of various cell lines, using TNFRSF10C antibody (STJ25886) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180.

Anti-TNFRSF10C antibody (150-238) (STJ25886)

SKU:
STJ25886

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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TNFRSF10C (150-238) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFRSF10C
Gene ID: 8794
Uniprot ID: TR10C_HUMAN
Immunogen Region: 150-238
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 150-238 of human TNFRSF10C (NP_003832.2).
Immunogen Sequence: VEEFGANATVETPAAEETMN TSPGTPAPAAEETMNTSPGT PAPAAEETMTTSPGTPAPAA EETMTTSPGTPAPAAEETMT TSPGTPASS
Tissue Specificity Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.
Post Translational Modifications N-glycosylated and O-glycosylated.
Function Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 10c
Antagonist Decoy Receptor For Trail/Apo-2l
Decoy Trail Receptor Without Death Domain
Decoy Receptor 1
Dcr1
Lymphocyte Inhibitor Of Trail
Tnf-Related Apoptosis-Inducing Ligand Receptor 3
Trail Receptor 3
Trail-R3
Trail Receptor Without An Intracellular Domain
Cd Antigen Cd263
Database Links Reactome: R-HSA-6803211
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 10c antibody
Anti-Antagonist Decoy Receptor For Trail/Apo-2l antibody
Anti-Decoy Trail Receptor Without Death Domain antibody
Anti-Decoy Receptor 1 antibody
Anti-Dcr1 antibody
Anti-Lymphocyte Inhibitor Of Trail antibody
Anti-Tnf-Related Apoptosis-Inducing Ligand Receptor 3 antibody
Anti-Trail Receptor 3 antibody
Anti-Trail-R3 antibody
Anti-Trail Receptor Without An Intracellular Domain antibody
Anti-Cd Antigen Cd263 antibody
Anti-TNFRSF10C antibody
Anti-DCR1 antibody
Anti-LIT antibody
Anti-TRAILR3 antibody
Anti-TRID antibody
Anti-UNQ321 antibody
Anti-PRO366 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance