• Western blot analysis of extracts of THP-1 cells, using TNFRSF10D antibody (STJ27889) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
  • Immunohistochemistry of paraffin-embedded mouse kidney using TNFRSF10D rabbit polyclonal antibody (STJ27889) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9. 0 before commencing with immunohistochemistry staining protocol.

Anti-TNFRSF10D antibody (257-386) (STJ27889)

SKU:
STJ27889

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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TNFRSF10D (257-386) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFRSF10D
Gene ID: 8793
Uniprot ID: TR10D_HUMAN
Immunogen Region: 257-386
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 257-386 of human TNFRSF10D (NP_003831.2).
Immunogen Sequence: VLFRRRSCPSRVPGAEDNAR NETLSNRYLQPTQVSEQEIQ GQELAELTGVTVELPEEPQR LLEQAEAEGCQRRRLLVPVN DADSADISTLLDASATLEEG HAKETIQDQLVGSEKLFYEE DEAGSATSCL
Tissue Specificity Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.
Function Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. it cannot but it can induce the NF-kappa-B pathway.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 10d
Decoy Receptor 2
Dcr2
Tnf-Related Apoptosis-Inducing Ligand Receptor 4
Trail Receptor 4
Trail-R4
Trail Receptor With A Truncated Death Domain
Cd Antigen Cd264
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-6803211
Reactome: R-HSA-75158
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 10d antibody
Anti-Decoy Receptor 2 antibody
Anti-Dcr2 antibody
Anti-Tnf-Related Apoptosis-Inducing Ligand Receptor 4 antibody
Anti-Trail Receptor 4 antibody
Anti-Trail-R4 antibody
Anti-Trail Receptor With A Truncated Death Domain antibody
Anti-Cd Antigen Cd264 antibody
Anti-TNFRSF10D antibody
Anti-DCR2 antibody
Anti-TRAILR4 antibody
Anti-TRUNDD antibody
Anti-UNQ251 antibody
Anti-PRO288 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance