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Anti-ADNP antibody

[STJ91502] Download PDF Print Data Sheet

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Product name Anti-ADNP antibody
Short Description Rabbit Polyclonal to ADNP.
Description ADNP is a protein encoded by the ADNP gene which is approximately 123,5 kDa. It is a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. It may also increase the viability of certain cell types through modulation of p53 activity. ADNP is widely expressed with strong expression in heart, skeletal muscle, kidney and placenta. Mutations in the ADNP gene may result in Helsmoortel-van der Aa syndrome. STJ91502 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ADNP protein.
Applications IHC-p, ELISA, WB
Dilution range WB 1:500-1:2000 / IHC 1:100-1:300 / ELISA 1:5000 /
Specificity ADNP Polyclonal Antibody detects endogenous levels of ADNP protein.
Protein Name Activity-dependent neuroprotector homeobox protein - ADNP - KIAA0784 - ADNP1 - activity dependent neuroprotector homeobox
Immunogen Synthesized peptide derived from human ADNP
Immunogen Region 80-160 aa, N-terminal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 23394 (Human) /
Gene Symbol ADNP
Molecular Weight 124 kDa
Database Links Human UniProt/Swiss-Prot:Q9H2P0 Mouse UniPort/Swiss-Prot: Q9Z103 Rat UniProt/Swiss-Port: Q9JKL8 Human Entrez Gene: 23394 Mouse Entrez Gene: 11538 Rat Entrez Gene: Rn.48777
Alternative Names ADNP / activity-dependent neuroprotector homeobox / A306_08501 antibody / activity-dependent neuroprotective protein antibody / Activity-dependent neuroprotector homeobox protein antibody / ADNP1 antibody / ADNP homeobox 1 antibody / AS27_03235 antibody / AS28_06952 antibody / D623_10026361 antibody / EGK_02296 antibody / H920_02727 antibody / HVDAS antibody / hypothetical protein antibody / M959_06559 antibody / MRD28 antibody / N300_15769 antibody / N301_06086 antibody / N302_00423 antibody / N303_02914 antibody / N305_05875 antibody / N306_01674 antibody / N307_09890 antibody / N308_06850 antibody / N309_09662 antibody / N312_12389 antibody / N320_05261 antibody / N321_08730 antibody / N324_01508 antibody / N325_08259 antibody / N326_12257 antibody / N327_08960 antibody / N328_04858 antibody / N329_05205 antibody / N330_12719 antibody / N331_06967 antibody / N332_07921 antibody / N333_11727 antibody / N334_04104 antibody / N336_02001 antibody / N341_04265 antibody / NAP peptide antibody / PANDA_000791 antibody / UY3_07003 antibody / Y1Q_012122 antibody / Y956_12897 antibody / Z169_03717 antibody
Function Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.
Cellular Localization Nucleus
Tissue Specificity Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissue

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