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Anti-ENT1 antibody

[STJ96396] Download PDF Print Data Sheet

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Product name Anti-ENT1 antibody
Short Description Rabbit Polyclonal to ENT1.
Description Rabbit Polyclonal to ENT1.
Applications ELISA, WB
Dilution range WB 1:500-1:2000 / ELISA 1:20000 /
Specificity ENT1 Polyclonal Antibody detects endogenous levels of ENT1 protein.
Protein Name Equilibrative nucleoside transporter 1 - SLC29A1 - ENT1 - solute carrier family 29 member 1 (Augustine blood group)
Immunogen Synthesized peptide derived from human ENT1.
Immunogen Region N-terminal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 2030 (Human) / 63959 (Mouse) / 63997 (Rat)
Gene Symbol SLC29A1
Molecular Weight 55 kDa
Database Links Human UniProt/Swiss-Prot:Q99808 Mouse UniPort/Swiss-Prot: Q9JIM1 Rat UniProt/Swiss-Port: O54698 Human Entrez Gene: 2030 Mouse Entrez Gene: 63959 Rat Entrez Gene: Rn.5814
Alternative Names SLC29A1 / solute carrier family 29 member 1 (Augustine blood group) / AS28_05174 antibody / CB1_001402088 antibody / EGK_14955 antibody / ent1 antibody / equilibrative NBMPR-sensitive nucleoside transporter antibody / equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter antibody / equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter antibody / Equilibrative nucleoside transporter 1 antibody / equilibrative nucleoside transporter 1 variant delta 11 antibody / hypothetical protein antibody / I79_008089 antibody / inhibitor-sensitive equilibrative nucleoside transporter 1 antibody / M91_00680 antibody / M959_06365 antibody / N300_12197 antibody / N301_13734 antibody / N302_08532 antibody / N303_14297 antibody / N305_05967 antibody / N306_02428 antibody / N307_11330 antibody / N309_05160 antibody / N310_00783 antibody / N311_02339 antibody / N312_01286 antibody / N320_07318 antibody / N321_05360 antibody / N324_07089 antibody / N325_06708 antibody / N326_10297 antibody / N327_04086 antibody / N328_04329 antibody / N330_10301 antibody / N332_07247 antibody / N333_12959 antibody / N334_05602 antibody / N335_07109 antibody / N336_07094 antibody / N340_09505 antibody / NBMPR-sensitive equilibrative nucleoside transporter antibody / nucleoside transporter / es-type antibody / PAL_GLEAN10025381 antibody / PANDA_002403 antibody / rENT1 antibody / solute carrier family 29 (equilibrative nucleoside transporter) antibody / solute carrier family 29 (equilibrative nucleoside transporter) / member 1 antibody / solute carrier family 29 member 1 antibody / solute carrier family 29 / member 1 antibody / solute carrier family 29 (nucleoside transporters) / member 1 antibody / TREES_T100007661 antibody / UY3_18407 antibody / Y1Q_019262 antibody / Y956_09380 antibody / Z169_14934 antibody
Function Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).
Post-translational Modifications Glycosylated.
Cellular Localization Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Predominantly localized in the basolateral membrane in polarized MDCK cells.
Tissue Specificity Detected in erythrocytes (at protein level). Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.

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