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Anti-GFAP antibody

[STJ96961] Download PDF Print Data Sheet
5-7 days

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Product name Anti-GFAP antibody
Short Description Mouse Monoclonal to GFAP.
Description GFAP is a protein encoded by the GFAP gene which is approximately 49,8 kDa. GFAP is localised to the cytoplasm. It is involved in signalling by ERBB4, the Jak-STAT signalling pathway, neural stem cell differentiation pathways, lineage-specific markers and ERK signalling. It is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. GFAP is expressed in the cells of the nervous system, kidney, blood, eye and heart. Mutations in the GFAP gene may result in Alexandra disease. STJ96961 was developed from clone 5C8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody binds endogenous GFAP.
Applications WB
Dilution range WB 1:2000-5000
Specificity The antibody detects endogenous GFAP proteins.
Protein Name Glial fibrillary acidic protein
GFAP
Immunogen Synthetic Peptide
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Mouse
Clonality Monoclonal
Clone ID 5C8
Reactivity Mouse, Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Isotype IgG1
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 2670
Gene Symbol GFAP
Database Links HGNC:4235
OMIM:137780
Alternative Names GFAP antibody
Glial fibrillary acidic protein antibody
GFAP antibody
Function GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Post-translational Modifications Phosphorylated by PKN1.
Cellular Localization Cytoplasm Note=Associated with intermediate filaments.
Tissue Specificity Expressed in cells lacking fibronectin.
Swiss-Prot Key P14136_HUMAN
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1
I am interested in this antibody in 0.3mg size, 1mg/mL. Would it be possible to change the storage buffer to PBS and not include sodium azide?
Question by: Guest on 11 Apr 2018 13:40:00
-3
Hello, thank you for your query. If you would like to place a custom order, the product should be at least 1 mg. There will be no additional cost for changing the storage buffer. Please contact us at info@stjohnslabs.com for further information.
Answer by: Customer Support on 11 Apr 2018 13:43:00

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