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Anti-GLI-1 antibody

[STJ98834] Download PDF Print Data Sheet

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Product name Anti-GLI-1 antibody
Short Description Rabbit Polyclonal to ACSS1 (Acetyl-K642).
Description Rabbit Polyclonal to ACSS1 (Acetyl-K642).
Applications ELISA, WB
Dilution range WB 1:500-2000 / ELISA 1:5000-20004
Specificity This antibody detects endogenous levels of ACSS1 (Acetyl-K642). It doesn't reacte with total protein.
Protein Name cDNA FLJ57539 - highly similar to Zinc finger protein GLI1 - ACSS1 - dJ568C11.3 - AceCS2L - MGC33843 - ACAS2L - acyl-CoA synthetase short-chain family member 1
Immunogen Synthesized Acetyl peptide derived from Human ACSS1
Immunogen Region K642
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 84532 (Human)
Gene Symbol ACSS1
Database Links Human Entrez Gene: 2735. Human Uniprot/Swiss-Prot:B4DNF7\n
Alternative Names GLI1 / GLI family zinc finger 1 / A306_15439 antibody / Anapl_14528 antibody / AS28_12396 antibody / ATH1 antibody / AV235269 antibody / CB1_000607006 antibody / detour antibody / dtr antibody / Gli antibody / Gli-1 antibody / gli1.1 antibody / GLI family zinc finger 1 / gene 1 antibody / GLI-Kruppel family member 1 antibody / GLI-Kruppel family member GLI1 antibody / glioma-associated oncogene 1 antibody / glioma-associated oncogene homolog antibody / glioma-associated oncogene homolog 1 antibody / glioma-associated oncogene homolog 1 (zinc finger protein) antibody / H920_14024 antibody / M959_12148 antibody / MDA_GLEAN10006657 antibody / N300_00696 antibody / N301_16112 antibody / N303_09849 antibody / N306_01794 antibody / N312_06214 antibody / N322_02717 antibody / N327_09790 antibody / N328_08121 antibody / N330_02474 antibody / N332_01382 antibody / N336_02801 antibody / N340_07593 antibody / N341_08598 antibody / oncogene GLI antibody / PAL_GLEAN10004860 antibody / PANDA_004120 antibody / TREES_T100018342 antibody / X-gli1 antibody / Y956_13690 antibody / Zfp5 antibody / Zfp-5 antibody / zinc finger DNA binding protein Gli-1 antibody / zinc finger protein 5 antibody / zinc finger protein GLI1 antibody
Function Important for maintaining normal body temperature during fasting and for energy homeostasis. Essential for energy expenditure under ketogenic conditions (By similarity). Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2).
Post-translational Modifications Reversibly acetylated on Lys-642. The acetyl-CoA synthase activity is inhibited by acetylation and activated by deacetylation.
Cellular Localization Mitochondrion matrix

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