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Anti-HIF-1 β/ARNT antibody

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Product name Anti-HIF-1 β/ARNT antibody
Short Description Mouse Monoclonal to HIF-1 β/ARNT (4C5).
Description Mouse Monoclonal to HIF-1 β/ARNT (4C5).
Applications IHC-p, WB
Dilution range WB 1:1000-2000 / IHC 1:100-200
Specificity HIF-1 β/ARNT Mouse Monoclonal Antibody (4C5) detects endogenous levels of HIF-1 β/ARNT
Protein Name Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor - nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta) - ARNT - HIF-1beta - bHLHe2 - aryl hydroc
Immunogen Recombinant Protein
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Mouse
Clonality Monoclonal
Clone ID 4C5
Reactivity Mouse
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Isotype IgG1
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 405 (Human) /
Gene Symbol ARNT
Database Links Human UniProt/Swiss-Prot:P27540 Mouse UniPort/Swiss-Prot: P53762 Rat UniProt/Swiss-Port: P41739 Human Entrez Gene: 405 Mouse Entrez Gene: 11863 Rat Entrez Gene: Rn.10520
Alternative Names ARNT / aryl hydrocarbon receptor nuclear translocator / AHA-1 antibody / arnt 1 antibody / ARNT1 antibody / arnt.2 antibody / ARNT protein antibody / ARNT_tv3 antibody / aryl hydrocarbon receptor nuclear translocater antibody / aryl-hydrocarbon receptor nuclear translocator antibody / aryl hydrocarbon receptor nuclear translocator 1 antibody / aryl hydrocarbon receptor nuclear translocator 2 antibody / aryl hydrocarbon receptor nuclear translocator homolog antibody / aryl hydrocarbon receptor nuclear translocator isoformX2 antibody / Aryl hydrocarbon receptor nuclear translocator-like protein antibody / AS27_07615 antibody / AS28_14122 antibody / bHLHe2 antibody / cathepsin K antibody / class E basic helix-loop-helix protein 2 antibody / CTSK antibody / D3Ertd557e antibody / dioxin receptor / nuclear translocator antibody / Drnt antibody / ESTM42 antibody / Hif1b antibody / hif-1beta antibody / HIF-1 beta antibody / HIF-1-beta antibody / HIF1-beta antibody / HIF1BETA antibody / hypothetical protein antibody / hypoxia-inducible factor 1 beta antibody / hypoxia-inducible factor 1-beta antibody / hypoxia-inducible factor 1 / beta subunit antibody / M959_14876 antibody / MDA_GLEAN10009665 antibody / N300_10906 antibody / N301_06023 antibody / N302_14933 antibody / N303_12375 antibody / N305_14617 antibody / N306_07281 antibody / N308_16163 antibody / N312_08235 antibody / N321_04534 antibody / N322_11291 antibody / N324_08439 antibody / N325_08013 antibody / N326_06937 antibody / N327_08484 antibody / N328_07591 antibody / N330_06138 antibody / N331_05963 antibody / N333_04635 antibody / N334_05362 antibody / N335_01009 antibody / N336_00423 antibody / N339_02583 antibody / N340_00704 antibody / N341_06724 antibody / rtARNT antibody / tango antibody / transcription factor protein antibody / W08714 antibody / xArnt antibody / Y1Q_019341 antibody / Y956_08221 antibody / Z169_10548 antibody
Function Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
Cellular Localization Nucleus.

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