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Anti-IL-13Rα1 antibody

[STJ93678] Download PDF Print Data Sheet

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Product name Anti-IL-13Rα1 antibody
Short Description Rabbit Polyclonal to IL-13Rα1.
Description Rabbit Polyclonal to IL-13Rα1.
Applications IHC-p, ELISA, IF, WB
Dilution range WB 1:500-1:2000 / IHC 1:100-1:300 / IF 1:200-1:1000 / ELISA 1:10000 /
Specificity IL-13Rα1 Polyclonal Antibody detects endogenous levels of IL-13Rα1 protein.
Protein Name Interleukin-13 receptor subunit alpha-1 - IL13RA1 - IL-13Ra - NR4 - CD213a1 - interleukin 13 receptor subunit alpha 1
Immunogen Synthesized peptide derived from human IL-13Rα1 around the non-phosphorylation site of Y405.
Immunogen Region 340-420 aa
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 3597 (Human) / 16164 (Mouse) /
Gene Symbol IL13RA1
Molecular Weight 49 kDa
Database Links Human UniProt/Swiss-Prot:P78552 Mouse UniPort/Swiss-Prot: O09030 Rat UniProt/Swiss-Port: Q561K3 Human Entrez Gene: 3597 Mouse Entrez Gene: 16164 Rat Entrez Gene: Rn.81210
Alternative Names IL13RA1 / interleukin 13 receptor subunit alpha 1 / A306_13810 antibody / Anapl_15093 antibody / AS27_07262 antibody / AS28_14196 antibody / cancer /testis antigen 19 antibody / CB1_000660029 antibody / CD213A1 antibody / CD213a1 antigen antibody / CT19 antibody / D623_10020216 antibody / GW7_08142 antibody / H920_04659 antibody / hypothetical protein antibody / Il13ra antibody / IL-13r[a] antibody / IL-13Ra antibody / il-13ra1 antibody / IL-13R-alpha-1 antibody / IL13 receptor alpha-1 chain antibody / IL-13 receptor subunit alpha-1 antibody / IL-13R subunit alpha-1 antibody / interleukin-13-binding protein antibody / interleukin 13 receptor alpha 1 antibody / interleukin 13 receptor / alpha 1 antibody / Interleukin-13 receptor alpha-1 antibody / Interleukin-13 receptor alpha-1 chain antibody / interleukin 13 receptor alpha chain 1 antibody / Interleukin-13 receptor subunit alpha-1 antibody / M91_15027 antibody / M959_02139 antibody / N300_15172 antibody / N301_11243 antibody / N302_09571 antibody / N303_14041 antibody / N305_09977 antibody / N306_08679 antibody / N307_13680 antibody / N308_01375 antibody / N309_06753 antibody / N310_09296 antibody / N311_12726 antibody / N312_12390 antibody / N320_07725 antibody / N321_07107 antibody / N322_09983 antibody / N324_02233 antibody / N326_09031 antibody / N327_07986 antibody / N328_08217 antibody / N330_06101 antibody / N331_06745 antibody / N333_10716 antibody / N334_03191 antibody / N335_02785 antibody / N339_05565 antibody / N340_01864 antibody / N341_01750 antibody / novel cytokine receptor 4 antibody / NR4 antibody / PAL_GLEAN10003565 antibody / PANDA_004175 antibody / Serine /threonine-protein kinase MST4 antibody / UY3_03566 antibody / Y956_03625 antibody / Z169_09904 antibody
Function Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Cellular Localization Membrane; Single-pass type I membrane protein.
Tissue Specificity Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.
Sequence and Domain Family The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.; The box 1 motif is required for JAK interaction and/or activation.

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