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Anti-Jagged1 antibody

[STJ96766] Download PDF Print Data Sheet

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Product name Anti-Jagged1 antibody
Description Rabbit Polyclonal to Jagged1.
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-p, WB
Immunogen Synthesized peptide derived from human Jagged1.
Gene ID 182 (Human) / 16449 (Mouse) / 29146 (Rat)
Dilution range WB 1:500-1:2000 / IHC-P 1:100-1:300 / ELISA 1:20000 /
Specificity Jagged1 Polyclonal Antibody detects endogenous levels of Jagged1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note For Research Use Only (RUO).
Protein Name Protein jagged-1 - JAG1 - AHD - AWS - HJ1 - CD339 - AGS - JAGL1 - jagged 1
Clonality Polyclonal
Conjugation Unconjugated
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration 1 mg/ml
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Database Links Human UniProt/Swiss-Prot:P78504 Mouse UniPort/Swiss-Prot: Q9QXX0 Rat UniProt/Swiss-Port: Q63722 Human Entrez Gene: 182 Mouse Entrez Gene: 16449 Rat Entrez Gene: Rn.88804
Alternative Names JAG1 / jagged 1 / A306_10556 antibody / ABE2 antibody / AGS antibody / AHD antibody / AS27_11330 antibody / AS28_01662 antibody / AWS antibody / CB1_000951001 antibody / CD339 antibody / C-Serate-1 protein antibody / D623_10032291 antibody / Gsfabe2 antibody / GW7_07255 antibody / H920_09536 antibody / HJ1 antibody / Htu antibody / hypothetical protein antibody / I79_000425 antibody / jagged1 antibody / jagged 1 (Alagille syndrome) antibody / Jagged-1 precursor isoform 3-like protein antibody / JAGL1 antibody / M91_15231 antibody / M959_07824 antibody / MDA_GLEAN10025066 antibody / N300_06370 antibody / N301_10998 antibody / N302_14352 antibody / N305_03536 antibody / N306_06619 antibody / N307_05877 antibody / N308_11928 antibody / N309_08113 antibody / N310_02520 antibody / N311_00701 antibody / N312_06046 antibody / N322_01082 antibody / N325_11791 antibody / N326_06045 antibody / N327_05149 antibody / N328_06301 antibody / N330_14535 antibody / N331_02636 antibody / N332_11228 antibody / N333_08213 antibody / N334_04221 antibody / N335_13280 antibody / N339_08777 antibody / N340_02557 antibody / Ozz antibody / PAL_GLEAN10024058 antibody / PANDA_007300 antibody / Protein jagged-1 antibody / Ser-1 antibody / serrate antibody / serrate-1 antibody / TREES_T100009915 antibody / UY3_11127 antibody / x-serrate-1 antibody / Y1Q_030215 antibody / Y956_14546 antibody / Z169_10201 antibody
Function Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).
Sequence and Domain Family The second EGF-like domain is atypical.
Cellular Localization Membrane; Single-pass type I membrane protein.

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