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Anti-Lamin B1 antibody

[STJ96938] Download PDF Print Data Sheet

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Product name Anti-Lamin B1 antibody
Description Mouse Monoclonal to Lamin B1.
Host Mouse
Reactivity Human, Mouse, Rat
Applications IP, WB
Immunogen Recombinant Protein
Gene ID 4001 (Human) / 16906 (Mouse) / 116685 (Rat)
Dilution range WB 1:2000-5000 / IP 1:200
Specificity The antibody detects endogenous Lamin B1 protein.
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Clone ID 7C11
Note For Research Use Only (RUO).
Protein Name Lamin-B1 - LMNB1 - lamin B1
Clonality Monoclonal
Conjugation Unconjugated
Isotype IgG1
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Database Links Human UniProt/Swiss-Prot:P20700 Mouse UniPort/Swiss-Prot: P14733 Rat UniProt/Swiss-Port: P70615 Human Entrez Gene: 4001 Mouse Entrez Gene: 16906 Rat Entrez Gene: Rn.11362
Alternative Names LMNB1 / lamin B1 / ADLD antibody / Anapl_17995 antibody / AS27_09747 antibody / AS28_00834 antibody / CB1_001532012 antibody / fc06g01 antibody / H920_06602 antibody / hypothetical protein antibody / I79_003938 antibody / lamin b antibody / lamin-b antibody / Lamin-B1 antibody / Lamin-B1-like protein antibody / Lamin-L(I) antibody / LMN antibody / lmn2 antibody / LMNB antibody / M91_03375 antibody / M959_02951 antibody / MDA_GLEAN10020664 antibody / N301_09389 antibody / N302_08926 antibody / N303_06544 antibody / N305_03236 antibody / N306_01916 antibody / N309_14235 antibody / N324_00503 antibody / N328_07823 antibody / N329_09369 antibody / N333_00556 antibody / N334_06646 antibody / N336_05195 antibody / N339_03548 antibody / PAL_GLEAN10025103 antibody / PANDA_006526 antibody / Y1Q_027424 antibody / Y956_06020 antibody
Function Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Post-translational Modifications B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.
Cellular Localization Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.

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