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Anti-MRE11 antibody

[STJ94194] Download PDF Print Data Sheet

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Product name Anti-MRE11 antibody
Short Description Rabbit Polyclonal to MRE11.
Description MRE11 is a protein encoded by the MRE11 gene which is approximately 80,5 kDa. MRE11 is localised to the nucleus and is involved in DNA double-strand break repair, cytosolic sensors of pathogen-associated DNA and telomere length maintenance. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. In conjunction with a DNA ligase, it promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. MRE11 is expressed in the nervous system, liver and blood. Mutations in the MRE11 gene may result in ataxia-telangiectasia-like disorder, Nijmegen breakage syndrome and hereditary breast ovarian cancer. STJ94194 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of MRE11 protein.
Applications IHC-p, ELISA, WB
Dilution range WB 1:500-1:2000 / IHC 1:100-1:300 / ELISA 1:20000 /
Specificity MRE11 Polyclonal Antibody detects endogenous levels of MRE11 protein.
Immunogen Synthesized peptide derived from human MRE11 around the non-phosphorylation site of S264.
Immunogen Region 200-280 aa
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Monkey, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 4361 (Human) / 17535 (Mouse) / 64046 (Rat)
Gene Symbol MRE11A
Molecular Weight 80 kDa
Database Links Human UniProt/Swiss-Prot:P49959 Mouse UniPort/Swiss-Prot: Q61216 Rat UniProt/Swiss-Port: Q9JIM0 Human Entrez Gene: 4361 Mouse Entrez Gene: 17535 Rat Entrez Gene: Rn.209040
Alternative Names MRE11A / MRE11 homolog A / double strand break repair nuclease / A306_02925 antibody / AS27_14219 antibody / AS28_02586 antibody / ATLD antibody / AT-like disease antibody / CB1_002256003 antibody / DNA recombination and repair protein antibody / Double-strand break repair protein MRE11 antibody / double-strand break repair protein MRE11A antibody / endo /exonuclease Mre11 antibody / fc38f05 antibody / GPR83 antibody / G protein-coupled receptor 83 antibody / H920_09356 antibody / HNGS1 antibody / hypothetical protein antibody / M91_07052 antibody / M959_00273 antibody / MDA_GLEAN10013027 antibody / meiotic recombination 11 homolog 1 antibody / meiotic recombination 11 homolog A antibody / meiotic recombination 11-like protein antibody / mmMRE11A antibody / MRE11 antibody / mre11-a antibody / MRE11A homolog A / double strand break repair nuclease antibody / Mre11b antibody / MRE11 double strand break repair nuclease A antibody / MRE11 homolog 1 antibody / MRE11 homolog A antibody / MRE11 homolog / double strand break repair nuclease A antibody / MRE11 meiotic recombination 11 homolog A antibody / MRE11 meiotic recombination 11 homolog A (S. cerevisiae) antibody / MRE11 meiotic recombination 11-like protein A antibody / N300_01701 antibody / N301_00100 antibody / N302_02009 antibody / N303_01984 antibody / N305_09190 antibody / N306_00124 antibody / N307_08210 antibody / N308_14524 antibody / N309_08300 antibody / N310_04933 antibody / N311_07414 antibody / N312_06930 antibody / N320_02151 antibody / N321_13914 antibody / N322_00939 antibody / N325_04691 antibody / N326_02100 antibody / N327_07168 antibody / N328_07177 antibody / N329_03764 antibody / N330_05503 antibody / N331_12251 antibody / N332_07622 antibody / N333_01836 antibody / N334_00519 antibody / N335_14162 antibody / N339_07469 antibody / N340_04204 antibody / N341_04535 antibody / PAL_GLEAN10013789 antibody / PANDA_020137 antibody / putative nuclease Mre11 antibody / TREES_T100004617 antibody / Y1Q_012599 antibody / Y956_13380 antibody / Z169_13084 antibody

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