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Anti-Myosin VI antibody

[STJ96437] Download PDF Print Data Sheet

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Product name Anti-Myosin VI antibody
Short Description Rabbit Polyclonal to Myosin VI.
Description Myosin VI is a protein encoded by the MYO6 gene which is approximately 149,6 kDa. Myosin VI is localised to the Golgi apparatus, nucleus and cytoplasm. It is involved in the PAK pathway, gap junction trafficking, actin nucleation and the RhoGDI pathway. It is a reverse-direction motor protein with ATPase activity that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. Myosin VI is expressed in most tissues including heart, brain, placenta, pancreas and spleen. Mutations in the MYO6 gene may result in deafness. STJ96437 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Myosin VI protein.
Applications IHC-p, ELISA, IF, WB
Dilution range WB 1:500-1:2000 / IHC-P 1:100-300 / ELISA 1:5000 /
Specificity Myosin VI Polyclonal Antibody detects endogenous levels of Myosin VI protein.
Protein Name Unconventional myosin-VI - MYO6 - KIAA0389 - DFNA22 - DFNB37 - myosin VI
Immunogen Synthesized peptide derived from human Myosin VI
Immunogen Region 40-120 aa, N-terminal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 4646 (Human) /
Gene Symbol MYO6
Molecular Weight 150 kDa
Database Links Human UniProt/Swiss-Prot:Q9UM54 Rat UniProt/Swiss-Port: D4A5I9 Human Entrez Gene: 4646 Mouse Entrez Gene: 17920
Alternative Names MYO6 / KIAA0389 / Unconventional myosin-VI / Unconventional myosin-6

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"Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice Ting-Yuan Liu, Yu-Chia Chen, Yuh-Jyh Jong, Huai-Jen Tsai, Chien-Chin Lee, Ya-Sian Chang, Jan-Gowth Chang, Yung-Fu Chang Published 11 January 2017.DOI: 10.1098/rsob.160303"