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Anti-Phospho-Dab1 (Y232) antibody

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Anti-Phospho-Dab1 (Y232) antibody

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Product name Anti-Phospho-Dab1 (Y232) antibody
Short Description Rabbit Polyclonal to Phospho-Dab1 (Y232).
Description Rabbit Polyclonal to Phospho-Dab1 (Y232).
Applications ELISA, IF, WB
Dilution range WB 1:500-1:2000 / IF 1:200-1:1000 / ELISA 1:20000 /
Specificity Phospho-Dab1 (Y232) Polyclonal Antibody detects endogenous levels of Dab1 protein only when phosphorylated at Y232.
Protein Name Disabled homolog 1 - DAB1 - DAB1 - reelin adaptor protein
Immunogen Synthesized peptide derived from human Dab1 around the phosphorylation site of Y232.
Immunogen Region 170-250 aa
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 8674 (Human) / 13131 (Mouse) / 266729 (Rat)
Gene Symbol DAB1
Molecular Weight 60 kDa
Database Links Human UniProt/Swiss-Prot:O75553 Mouse UniPort/Swiss-Prot: P97318 Rat UniProt/Swiss-Port: Q8CJH2 Human Entrez Gene: 8674 Mouse Entrez Gene: 13131 Rat Entrez Gene: Rn.206534
Alternative Names DAB1 / DAB1 / reelin adaptor protein / A306_13548 antibody / Anapl_17024 antibody / AS27_01051 antibody / AS28_04139 antibody / CB1_001009008 antibody / D623_10020951 antibody / DAB-1 antibody / Dab reelin signal transducer 1 antibody / Dab / reelin signal transducer / homolog 1 antibody / Dab / reelin signal transducer / homolog 1 (Drosophila) antibody / Dab / reelin signal transducer / -like protein 1 antibody / disabled-1 antibody / Disabled 1 antibody / Disabled 1-like protein antibody / disabled homolog 1 antibody / Disabled-like 1 antibody / disabled-like 1-like protein antibody / Disabled like protein 1 antibody / Disabled-like protein 1 antibody / H920_14760 antibody / hypothetical protein antibody / I79_000980 antibody / M91_03917 antibody / M959_09866 antibody / N300_00614 antibody / N301_03240 antibody / N302_09214 antibody / N303_09409 antibody / N305_06902 antibody / N306_02461 antibody / N307_09823 antibody / N308_14853 antibody / N310_09727 antibody / N311_10242 antibody / N312_03928 antibody / N320_11658 antibody / N321_01582 antibody / N322_13187 antibody / N325_00763 antibody / N326_01174 antibody / N327_13107 antibody / N328_12913 antibody / N329_09504 antibody / N330_04664 antibody / N331_09984 antibody / N332_12570 antibody / N333_11060 antibody / N334_07228 antibody / N335_07223 antibody / N336_07293 antibody / N339_11820 antibody / N340_08765 antibody / N341_12387 antibody / PAL_GLEAN10023801 antibody / PANDA_017185 antibody / scm antibody / scr antibody / scrambler antibody / UY3_06331 antibody / Y1Q_010118 antibody / Y956_08837 antibody / yot antibody / yotari antibody / Z169_03049 antibody
Function Adapter molecule functioning in neural development. May regulate SIAH1 activity (By similarity).
Post-translational Modifications Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons. Also phosphorylated on Ser-524 independently of reelin signaling.
Sequence and Domain Family The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.

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