Anti-Phospho-Dab1 (Y232) antibody

[STJ90682] Download PDF Print Data Sheet

Lead 5-7 days

100μl £150.00
200μl £180.00
50μl £99.00

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General Information
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Product name	Anti-Phospho-Dab1 (Y232) antibody
Description	Rabbit polyclonal to Phospho-Dab1 (Y232).
Applications	ELISA, IF, WB
Dilution range	WB 1:500-1:2000 IF 1:200-1:1000 ELISA 1:20000
Specificity	Phospho-Dab1 (Y232) Polyclonal Antibody detects endogenous levels of Dab1 protein only when phosphorylated at Y232.
Protein Name	Disabled homolog 1
Immunogen	Synthesized peptide derived from human Dab1 around the phosphorylation site of Y232.
Immunogen Region	170-250 aa
Storage Instruction	Store at -20°C, and avoid repeat freeze-thaw cycles.
Note	For Research Use Only (RUO).

Host	Rabbit
Clonality	Polyclonal
Reactivity	Mouse, Rat, Human
Conjugation	Unconjugated
Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype	IgG
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Gene ID	1600
Gene Symbol	DAB1
Molecular Weight	60 kDa
Database Links	HGNC:2661 OMIM:603448
Alternative Names	Anti-Phospho-Dab1 (Y232) antibody
Function	Adapter molecule functioning in neural development. May regulate SIAH1 activity .
Post-translational Modifications	Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons. Also phosphorylated on Ser-524 independently of reelin signaling.
Sequence and Domain Family	The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
Swiss-Prot Key	O75553_HUMAN

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