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Anti-TGFβ1 antibody

[STJ95997] Download PDF Print Data Sheet

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Product name Anti-TGFβ1 antibody
Short Description Rabbit Polyclonal to TGFβ1.
Description TGF-beta 1 is a protein encoded by the TGFB1 gene which is approximately 44,3 kDa. TGF-beta 1 is secreted into the extracellular space and matrix and is involved in apoptotic pathways in synovial fibroblasts, SMAD2/3 MH2 domain mutants in cancer, Th17 differentiation pathway, GPCR pathway and ERK signalling. This protein falls under the TGF-beta superfamily which bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. It is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. TGF-beta 1 is highly expressed in bone. Mutations in the TGFB1 gene may result in Camurati-Engelmann disease and Cystic Fibrosis, Renal Fibrosis. STJ95997 was developed from clone 5D2. It was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This mouse monoclonal antibody detects endogenous levels of TGF-beta 1.
Applications IHC-p, ELISA, IF, WB
Dilution range WB 1:500-1:2000 / IHC 1:100-1:300 / IF 1:200-1:1000 / ELISA 1:20000 /
Specificity TGFβ1 Polyclonal Antibody detects endogenous levels of TGFβ1 protein.
Protein Name Transforming growth factor beta-1 - TGFB1 - CED - TGFbeta - TGFB - DPD1 - transforming growth factor beta 1
Immunogen Synthesized peptide derived from human TGFβ1
Immunogen Region 310-390 aa, C-terminal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 7040 (Human) / 21803 (Mouse) / 59086 (Rat)
Gene Symbol TGFB1
Molecular Weight 44 kDa
Database Links Human UniProt/Swiss-Prot:P01137 Mouse UniPort/Swiss-Prot: P04202 Rat UniProt/Swiss-Port: P17246 Human Entrez Gene: 7040 Mouse Entrez Gene: 21803 Rat Entrez Gene: Rn.40136
Alternative Names TGFB1 / transforming growth factor beta 1 / ced antibody / dpd1 antibody / H920_05001 antibody / interleukin TGF beta antibody / lap antibody / latency-associated peptide antibody / PAL_GLEAN10000575 antibody / prepro-transforming growth factor beta-1 antibody / Tgfb antibody / Tgfb-1 antibody / TGFB4 antibody / tgfb5 antibody / tgfbeta antibody / tgf beta antibody / tgf-beta antibody / TGFbeta1 antibody / TGF-beta1 antibody / TGF-beta 1 antibody / TGF-BETA-1 antibody / TGF-beta4 antibody / tgf-beta 5 antibody / TGF-beta5 antibody / TGF-beta-5 antibody / tissue growth factor-beta4 antibody / transforming gorwth factor-Beta5 antibody / transforming growth factor-B5 antibody / transforming growth factor beta antibody / transforming growth factor-beta antibody / transforming growth factor beta1 antibody / transforming growth factor-beta 1 antibody / transforming growth factor-beta-1 antibody / transforming growth factor / beta 1 antibody / transforming growth factor / beta-1 antibody / Transforming growth factor beta-1 antibody / transforming growth factor / beta 1 (Camurati-Engelmann disease) antibody / transforming growth factor beta 1 precursor-like protein antibody / transforming growth factor beta 4 antibody / transforming growth factor-beta 5 antibody


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