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Anti-V-ATPase H antibody

[STJ96226] Download PDF Print Data Sheet

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Product name Anti-V-ATPase H antibody
Short Description Rabbit Polyclonal to V-ATPase H.
Description V-ATPase H is a protein encoded by the ATP6V1H gene which is approximately 55,9 kDa. V-ATPase H is localised to the cytosol. It is involved in insulin receptor recycling and innate immune system. It is a multi-subunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. V-ATPase H is widely expressed. Mutations in the ATP6V1H gene may result in an involvement in the HIV life cycle. STJ96226 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of V-ATPase H protein.
Applications IHC-p, ELISA, WB
Dilution range WB 1:500-1:2000 / IHC 1:100-1:300 / ELISA 1:20000 /
Specificity V-ATPase H Polyclonal Antibody detects endogenous levels of V-ATPase H protein.
Protein Name V-type proton ATPase subunit H - ATP6V1H - CGI-11 - SFD - VMA13 - SFDalpha - SFDbeta - ATPase H+ transporting V1 subunit H
Immunogen Synthesized peptide derived from human V-ATPase H
Immunogen Region 310-390 aa, Internal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 51606 (Human) / 108664 (Mouse) /
Gene Symbol ATP6V1H
Molecular Weight 55 kDa
Database Links Human UniProt/Swiss-Prot:Q9UI12 Mouse UniPort/Swiss-Prot: Q8BVE3 Rat UniProt/Swiss-Port: Q5XIL1 Human Entrez Gene: 51606 Mouse Entrez Gene: 108664 Rat Entrez Gene: Rn.21454
Alternative Names ATP6V1H / ATPase H+ transporting V1 subunit H / 54 kDa vacuolar H(+)-ATPase subunit antibody / A306_04326 antibody / AS27_01778 antibody / AS28_15116 antibody / ATPase / H+ transporting / lysosomal 50 /57kDa / V1 subunit H antibody / ATPase / H+ transporting / lysosomal V1 subunit H antibody / ATPase / H+ transporting / lysosomal / V1 subunit H antibody / CB1_001437031 antibody / CGI-11 antibody / chunp6890 antibody / D623_10013256 antibody / GW7_02847 antibody / H+ transporting ATPase lysosomal V1 subunit H antibody / hypothetical protein antibody / I79_013987 antibody / M959_00890 antibody / MDA_GLEAN10024585 antibody / MSTP042 antibody / N300_12876 antibody / N301_08786 antibody / N302_13355 antibody / N303_11154 antibody / N306_12396 antibody / N308_01246 antibody / N309_15487 antibody / N310_10773 antibody / N311_08543 antibody / N312_01725 antibody / N320_01830 antibody / N324_01822 antibody / N327_06132 antibody / N328_05864 antibody / N329_07622 antibody / N331_12332 antibody / N333_06420 antibody / N334_12498 antibody / N335_13437 antibody / N336_02230 antibody / N339_07160 antibody / N340_12667 antibody / NBP1 antibody / nef-binding protein 1 antibody / PAL_GLEAN10019244 antibody / PANDA_019837 antibody / protein VMA13 homolog antibody / SFD antibody / SFDalpha antibody / SFDbeta antibody / TREES_T100010531 antibody / unm hi923 antibody / un-named hi923 antibody / UY3_11080 antibody / vacuolar ATPase subunit H antibody / vacuolar ATP synthase subunit H antibody / vacuolar proton pump H subunit antibody / Vacuolar proton pump subunit H antibody / vacuolar proton pump subunit SFD antibody / V-ATPASE antibody / V-ATPase 50 /57 kDa subunits antibody / V-ATPase H subunit antibody / V-ATPase subunit H antibody / VMA13 antibody / V-type proton ATPase subunit H antibody / Y1Q_004471 antibody / Y956_15603 antibody / Z169_08707 antibody
Function Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes.
Tissue Specificity Widely expressed.

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