SHOPPING BASKET: 0 item(s) - £0.00  

You have no items in your shopping cart.

Anti-V-ATPase H antibody

[STJ96226] Download PDF Print Data Sheet
5-7 days

* Required Fields

£0.00
Product name Anti-V-ATPase H antibody
Short Description Rabbit polyclonal to V-ATPase H.
Description V-ATPase H is a protein encoded by the ATP6V1H gene which is approximately 55,9 kDa. V-ATPase H is localised to the cytosol. It is involved in insulin receptor recycling and innate immune system. It is a multi-subunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. V-ATPase H is widely expressed. Mutations in the ATP6V1H gene may result in an involvement in the HIV life cycle. STJ96226 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of V-ATPase H protein.
Applications ELISA, IHC-p, WB
Dilution range WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
Specificity V-ATPase H Polyclonal Antibody detects endogenous levels of V-ATPase H protein.
Protein Name V-type proton ATPase subunit H
V-ATPase subunit H
Nef-binding protein 1
NBP1
Protein VMA13 homolog
V-ATPase 50/57 kDa subunits
Vacuolar proton pump subunit H
Vacuolar proton pump subunit SFD
Immunogen Synthesized peptide derived from human V-ATPase H
Immunogen Region 310-390 aa, Internal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Mouse, Human
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 51606
Gene Symbol ATP6V1H
Molecular Weight 55 kDa
Database Links HGNC:18303
OMIM:608861
Alternative Names Anti-V-ATPase H antibody
Function Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system . Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes.
Tissue Specificity Widely expressed.
Swiss-Prot Key Q9UI12_HUMAN
Bad Good
Enter the code in the box below:

Ask us a question

No questions yet. Be the first to ask the question!

Tags:

Use spaces to separate tags. Use single quotes (') for phrases.