Anti-HDGF antibody (STJ27300)

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General information

Product name Anti-HDGF antibody
Description This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Host Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, IP, RIP
Immunogen Recombinant protein of human HDGF.
Gene ID 3068
Dilution range WB 1:500-1:2000; IHC 1:50-1:200; IF 1:50-1:200; IP 1:20-1:50R; IP 1:20-1:50
Purification Affinity purification
Note For research use only.
Protein Name HDGF - Hepatoma-derived growth factor - Homo sapiens (Human) - HDGF protein

Product properties

Clonality Polyclonal
Conjugation Unconjugated
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Molecular Weight N/A
Concentration 1 mg/ml
Storage Instruction Store at -20°C. Avoid repeated freeze/thaw cycles.

Target

Database Links Genecards: 3068
Alternative names
HDGF / hepatoma-derived growth factor / CB1_000161010 antibody, D3Ertd299e antibody, DNA repair protein RAD51 homolog 1 antibody, DNA repair protein RAD51-like protein 1 antibody, hepatoma-derived growth factor (high-mobility group protein 1-like) antibody, high mobility group protein 1-like 2 antibody, hmg1l2 antibody, hypothetical protein antibody, I79_009588 antibody, M959_15089 antibody, N301_09771 antibody, N303_11535 antibody, N305_02976 antibody, N309_00892 antibody, N310_02580 antibody, N321_10506 antibody, N322_06097 antibody, N325_00109 antibody, N329_10140 antibody, N330_09635 antibody, N340_09362 antibody, PAL_GLEAN10005319 antibody, PANDA_016708 antibody, RAD51 antibody, TREES_T100016112 antibody, UY3_11561 antibody, Y1Q_028515 antibody
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Function Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.
Tissue Specificity Ubiquitous.
Sequence and Domain Family The PWWP domain harbors the heparin-binding sites and is responsible for DNA-binding, while the C-terminal region is essentially unstructured.
Post-translational Modifications Sumoylated with SUMO1. Sumoylation prevents binding to chromatin.
Cellular Localization Cytoplasm

Product images-applications

Western blot analysis of extracts of various cell lines, using HDGF antibody.

Immunohistochemistry of paraffin-embedded rat liver using HDGF antibody at dilution of 1:100 (x400 lens).

Immunohistochemistry of paraffin-embedded rat brain using HDGF antibody at dilution of 1:100 (x400 lens).

Immunohistochemistry of paraffin-embedded rat kidney using HDGF antibody at dilution of 1:100 (x400 lens).

Immunofluorescence analysis of U20S cell using HDGF antibody. Blue: DAPI for nuclear staining.

Immunofluorescence analysis of A549 cell using HDGF antibody.

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