Anti-ACADL Antibody

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Product name Anti-ACADL Antibody
Short Description Rabbit polyclonal against ACADL
Description The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.
Applications IF, IHC, WB
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Long-chain specific acyl-CoA dehydrogenase
mitochondrial
LCAD
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 31-210 of human ACADL (NP_001599.1).
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB IHC IF
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 33
Gene Symbol ACADL
Molecular Weight 47.656 kDa
Database Links HGNC:88
OMIM:201475
Reactome:R-HSA-77285
Alternative Names Long-chain specific acyl-CoA dehydrogenase
mitochondrial
LCAD
Post-translational Modifications Acetylation at Lys-318 and Lys-322 in proximity of the cofactor-binding sites strongly reduces catalytic activity, These sites are deacetylated by SIRT3 ,
Cellular Localization Mitochondrion matrix
Swiss-Prot Key P28330
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