| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ACTR6 (237-396) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ACTR6 |
| Gene ID: |
64431 |
| Uniprot ID: |
ARP6_HUMAN |
| Immunogen Region: |
237-396 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 237-396 of human ACTR6 (NP_071941.1). |
| Immunogen Sequence: |
VLPDFSTIKKGFCKPREEMV LSGKYKSGEQILRLANERFA VPEILFNPSDIGIQEMGIPE AIVYSIQNLPEEMQPHFFKN IVLTGGNSLFPGFRDRVYSE VRCLTPTDYDVSVVLPENPI TYAWEGGKLISENDDFEDMV VTREDYEENGHSVCEEKFDI |
| Function | Required for formation and/or maintenance of proper nucleolar structure and function. Plays a dual role in the regulation of ribosomal DNA (rDNA) transcription. In the presence of high glucose, maintains active rDNA transcription through H2A.Z deposition and under glucose starvation, is required for the repression of rDNA transcription, and this function may be independent of H2A.Z. |
| Protein Name | Actin-Related Protein 6Harp6Harpx |
| Cellular Localisation | CytoplasmCytoskeletonNucleusNucleolusColocalizes With Hp1 Family Proteins At Pericentric Heterochromatin |
| Alternative Antibody Names | Anti-Actin-Related Protein 6 antibodyAnti-Harp6 antibodyAnti-Harpx antibodyAnti-ACTR6 antibodyAnti-CDA12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
