• Western blot analysis of extracts of various cell lines, using BMPR1A antibody (STJ22819) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of extracts of various cell lines, using BMPR1A Rabbit polyclonal antibody (STJ22819) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-BMPR1A antibody (24-200) (STJ22819)

SKU:
STJ22819

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BMPR1A (24-200) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BMPR1A
Gene ID: 657
Uniprot ID: BMR1A_HUMAN
Immunogen Region: 24-200
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-200 of human BMPR1A (NP_004320.2).
Immunogen Sequence: QNLDSMLHGTGMKSDSDQKK SENGVTLAPEDTLPFLKCYC SGHCPDDAINNTCITNGHCF AIIEEDDQGETTLASGCMKY EGSDFQCKDSPKAQLRRTIE CCRTNLCNQYLQPTLPPVVI GPFFDGSIRWLVLLISMAVC IIAMIIFSSCFCYKHYCKSI SSRRRYNRDLEQDEAFI
Tissue Specificity Highly expressed in skeletal muscle.
Post Translational Modifications Glycosylated.
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. May promote the expression of HAMP, potentially via its interaction with BMP2.
Protein Name Bone Morphogenetic Protein Receptor Type-1a
Bmp Type-1a Receptor
Bmpr-1a
Activin Receptor-Like Kinase 3
Alk-3
Serine/Threonine-Protein Kinase Receptor R5
Skr5
Cd Antigen Cd292
Database Links Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Surface
Alternative Antibody Names Anti-Bone Morphogenetic Protein Receptor Type-1a antibody
Anti-Bmp Type-1a Receptor antibody
Anti-Bmpr-1a antibody
Anti-Activin Receptor-Like Kinase 3 antibody
Anti-Alk-3 antibody
Anti-Serine/Threonine-Protein Kinase Receptor R5 antibody
Anti-Skr5 antibody
Anti-Cd Antigen Cd292 antibody
Anti-BMPR1A antibody
Anti-ACVRLK3 antibody
Anti-ALK3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance