• Western blot analysis of extracts of various cell lines, using BTC antibody (STJ22842) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-BTC antibody (32-178) (STJ22842)

SKU:
STJ22842

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BTC (32-178) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BTC
Gene ID: 685
Uniprot ID: BTC_HUMAN
Immunogen Region: 32-178
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 32-178 of human BTC (NP_001720.1).
Immunogen Sequence: DGNSTRSPETNGLLCGDPEE NCAATTTQSKRKGHFSRCPK QYKHYCIKGRCRFVVAEQTP SCVCDEGYIGARCERVDLFY LRGDRGQILVICLIAVMVVF IILVIGVCTCCHPLRKRRKR KKKEEEMETLGKDITPINED IEETNIA
Tissue Specificity Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.
Function Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Protein Name Probetacellulin Cleaved Into - Betacellulin
Btc
Database Links Reactome: R-HSA-1227986
Reactome: R-HSA-1236394
Reactome: R-HSA-1250196
Reactome: R-HSA-1250342
Reactome: R-HSA-1250347
Reactome: R-HSA-1251985
Reactome: R-HSA-1257604
Reactome: R-HSA-177929
Reactome: R-HSA-179812
Reactome: R-HSA-180292
Reactome: R-HSA-180336
Reactome: R-HSA-182971
Reactome: R-HSA-1963640
Reactome: R-HSA-1963642
Reactome: R-HSA-212718
Reactome: R-HSA-2219530
Reactome: R-HSA-5638303
Reactome: R-HSA-5673001
Reactome: R-HSA-6785631
Reactome: R-HSA-6811558
Reactome: R-HSA-8847993
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Reactome: R-HSA-8863795
Reactome: R-HSA-9009391
Reactome: R-HSA-9634638
Reactome: R-HSA-9664565
Reactome: R-HSA-9665686
Cellular Localisation Betacellulin: Secreted
Extracellular Space
Probetacellulin: Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Probetacellulin Cleaved Into - Betacellulin antibody
Anti-Btc antibody
Anti-BTC antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance