• Western blot analysis of extracts of various cell lines, using Carbonic Anhydrase 2 (CA2) antibody (STJ22856) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-CA2 antibody (1-250) (STJ22856)

SKU:
STJ22856

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CA2 (1-250) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CA2
Gene ID: 760
Uniprot ID: CAH2_HUMAN
Immunogen Region: 1-250
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human Carbonic Anhydrase 2 (CA2) (NP_000058.1).
Immunogen Sequence: MSHHWGYGKHNGPEHWHKDF PIAKGERQSPVDIDTHTAKY DPSLKPLSVSYDQATSLRIL NNGHAFNVEFDDSQDKAVLK GGPLDGTYRLIQFHFHWGSL DGQGSEHTVDKKKYAAELHL VHWNTKYGDFGKAVQQPDGL AVLGIFLKVGSAKPGLQKVV DVLDSIKTKGKSADFTNFDP RGLLPESLDYWTYPGSLTTP PLLECVTWIVLKEPISVSSE QVLKFRKLNFNGEGEPEEL
Function Catalyzes the reversible hydration of carbon dioxide. Can also hydrate cyanamide to urea. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. Essential for bone resorption and osteoclast differentiation. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption.
Protein Name Carbonic Anhydrase 2
Carbonate Dehydratase Ii
Carbonic Anhydrase C
Cac
Carbonic Anhydrase Ii
Ca-Ii
Cyanamide Hydratase Ca2
Database Links Reactome: R-HSA-1237044
Reactome: R-HSA-1247673
Reactome: R-HSA-1475029
Cellular Localisation Cytoplasm
Cell Membrane
Colocalized With Slc26a6 At The Surface Of The Cell Membrane In Order To Form A Bicarbonate Transport Metabolon
Displaced From The Cytosolic Surface Of The Cell Membrane By Pkc In Phorbol Myristate Acetate (Pma)-Induced Cells
Alternative Antibody Names Anti-Carbonic Anhydrase 2 antibody
Anti-Carbonate Dehydratase Ii antibody
Anti-Carbonic Anhydrase C antibody
Anti-Cac antibody
Anti-Carbonic Anhydrase Ii antibody
Anti-Ca-Ii antibody
Anti-Cyanamide Hydratase Ca2 antibody
Anti-CA2 antibody

Information sourced from Uniprot.org

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