| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CCL16 (1-120) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CCL16 |
| Gene ID: |
6360 |
| Uniprot ID: |
CCL16_HUMAN |
| Immunogen Region: |
1-120 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human CCL16 (NP_004581.1). |
| Immunogen Sequence: |
MKVSEAALSLLVLILIITSA SRSQPKVPEWVNTPSTCCLK YYEKVLPRRLVVGYRKALNC HLPAIIFVTKRNREVCTNPN DDWVQEYIKDPNLPLLPTRN LSTVKIITAKNGQPQLLNSQ |
| Tissue Specificity | Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones. |
| Function | Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. |
| Protein Name | C-C Motif Chemokine 16Chemokine Cc-4Hcc-4Chemokine LecIl-10-Inducible ChemokineLcc-1Liver-Expressed ChemokineLymphocyte And Monocyte ChemoattractantLmcMonotactin-1Mtn-1Ncc-4Small-Inducible Cytokine A16 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 16 antibodyAnti-Chemokine Cc-4 antibodyAnti-Hcc-4 antibodyAnti-Chemokine Lec antibodyAnti-Il-10-Inducible Chemokine antibodyAnti-Lcc-1 antibodyAnti-Liver-Expressed Chemokine antibodyAnti-Lymphocyte And Monocyte Chemoattractant antibodyAnti-Lmc antibodyAnti-Monotactin-1 antibodyAnti-Mtn-1 antibodyAnti-Ncc-4 antibodyAnti-Small-Inducible Cytokine A16 antibodyAnti-CCL16 antibodyAnti-ILINCK antibodyAnti-NCC4 antibodyAnti-SCYA16 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
