| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CCS (1-274) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CCS |
| Gene ID: |
9973 |
| Uniprot ID: |
CCS_HUMAN |
| Immunogen Region: |
1-274 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-274 of human CCS (NP_005116.1). |
| Immunogen Sequence: |
MASDSGNQGTLCTLEFAVQM TCQSCVDAVRKSLQGVAGVQ DVEVHLEDQMVLVHTTLPSQ EVQALLEGTGRQAVLKGMGS GQLQNLGAAVAILGGPGTVQ GVVRFLQLTPERCLIEGTID GLEPGLHGLHVHQYGDLTNN CNSCGNHFNPDGASHGGPQD SDRHRGDLGNVRADADGRAI FRMEDEQLKVWDVIGRSLII DEGEDDLGRGGHPLSKITGN SGERLACGIIARSAGLFQN |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Ubiquitinion by XIAP/BIRC4 leads to enhancement of its chaperone activity toward its physiologic target, SOD1, rather than proteasomal degradation. XIAP/BIRC4 preferentially ubiquitinates at Lys-241. |
| Function | Delivers copper to copper zinc superoxide dismutase (SOD1). |
| Protein Name | Copper Chaperone For Superoxide DismutaseSuperoxide Dismutase Copper Chaperone |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Copper Chaperone For Superoxide Dismutase antibodyAnti-Superoxide Dismutase Copper Chaperone antibodyAnti-CCS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
