• Western blot analysis of extracts of various cell lines, using CFHR1 antibody (STJ23106) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-CFHR1 antibody (151-330) (STJ23106)

SKU:
STJ23106

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CFHR1 (151-330) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CFHR1
Gene ID: 3078
Uniprot ID: FHR1_HUMAN
Immunogen Region: 151-330
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 151-330 of human CFHR1 (NP_002104.2).
Immunogen Sequence: PTVQNAHILSRQMSKYPSGE RVRYECRSPYEMFGDEEVMC LNGNWTEPPQCKDSTGKCGP PPPIDNGDITSFPLSVYAPA SSVEYQCQNLYQLEGNKRIT CRNGQWSEPPKCLHPCVISR EIMENYNIALRWTAKQKLYL RTGESAEFVCKRGYRLSSRS HTLRTTCWDGKLEYPTCAKR
Tissue Specificity Expressed by the liver and secreted in plasma.
Post Translational Modifications N-glycosylated. Two forms are observed.one with a single side chain and the other with two.
Function Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.
Protein Name Complement Factor H-Related Protein 1
Fhr-1
H Factor-Like Protein 1
Fhl-1
H-Factor-Like 1
H36
Database Links Reactome: R-HSA-977606
Cellular Localisation Secreted
Alternative Antibody Names Anti-Complement Factor H-Related Protein 1 antibody
Anti-Fhr-1 antibody
Anti-H Factor-Like Protein 1 antibody
Anti-Fhl-1 antibody
Anti-H-Factor-Like 1 antibody
Anti-H36 antibody
Anti-CFHR1 antibody
Anti-CFHL antibody
Anti-CFHL1 antibody
Anti-CFHL1P antibody
Anti-CFHR1P antibody
Anti-FHR1 antibody
Anti-HFL1 antibody
Anti-HFL2 antibody

Information sourced from Uniprot.org

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