| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CNDP2 (1-210) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CNDP2 |
| Gene ID: |
55748 |
| Uniprot ID: |
CNDP2_HUMAN |
| Immunogen Region: |
1-210 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human CNDP2 (NP_060705.2). |
| Immunogen Sequence: |
MAALTTLFKYIDENQDRYIK KLAKWVAIQSVSAWPEKRGE IRRMMEVAAADVKQLGGSVE LVDIGKQKLPDGSEIPLPPI LLGRLGSDPQKKTVCIYGHL DVQPAALEDGWDSEPFTLVE RDGKLYGRGSTDDKGPVAGW INALEAYQKTGQEIPVNVRF CLEGMEESGSEGLDELIFAR KDTFFKDVDYVCISDNYWLG KKKPCITYGL |
| Tissue Specificity | Isoform 1: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes. Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level). Isoform 2: Broadly expressed in fetal tissues. Expressed in adult liver and placenta. |
| Function | Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. Mediates threonyl dipeptide catabolism in a tissue-specific way. Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism. Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis. Plays a role in the regulation of cell cycle arrest and apoptosis. |
| Protein Name | Cytosolic Non-Specific DipeptidaseCndp Dipeptidase 2Glutamate Carboxypeptidase-Like Protein 1Peptidase AThreonyl Dipeptidase |
| Database Links | Reactome: R-HSA-174403Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cytosolic Non-Specific Dipeptidase antibodyAnti-Cndp Dipeptidase 2 antibodyAnti-Glutamate Carboxypeptidase-Like Protein 1 antibodyAnti-Peptidase A antibodyAnti-Threonyl Dipeptidase antibodyAnti-CNDP2 antibodyAnti-CN2 antibodyAnti-CPGL antibodyAnti-HEL-S-13 antibodyAnti-PEPA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
