• Western blot analysis of extracts of various cell lines, using CNTFR antibody (STJ23187) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-CNTFR antibody (90-342) (STJ23187)

SKU:
STJ23187

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CNTFR (90-342) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:400-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CNTFR
Gene ID: 1271
Uniprot ID: CNTFR_HUMAN
Immunogen Region: 90-342
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 90-342 of human CNTFR (NP_671693.1).
Immunogen Sequence: FHRDSWHLRHQVLLHVGLPP REPVLSCRSNTYPKGFYCSW HLPTPTYIPNTFNVTVLHGS KIMVCEKDPALKNRCHIRYM HLFSTIKYKVSISVSNALGH NATAITFDEFTIVKPDPPEN VVARPVPSNPRRLEVTWQTP STWPDPESFPLKFFLRYRPL ILDQWQHVELSDGTAHTITD AYAGKEYIIQVAAKDNEIGT WSDWSVAAHATPWTEEPRHL TTEAQAAETTTSTTSSLAP
Tissue Specificity Nervous system and skeletal muscle.
Function Binds to CNTF. The alpha subunit provides the receptor specificity. Receptor for heterodimeric neurotropic cytokine composed of CLCF1/CLC and CRLF1/CLF-1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and IL27RA/WSX1.
Protein Name Ciliary Neurotrophic Factor Receptor Subunit Alpha
Cntf Receptor Subunit Alpha
Cntfr-Alpha
Database Links Reactome: R-HSA-6788467
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Ciliary Neurotrophic Factor Receptor Subunit Alpha antibody
Anti-Cntf Receptor Subunit Alpha antibody
Anti-Cntfr-Alpha antibody
Anti-CNTFR antibody

Information sourced from Uniprot.org

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