• Western blot analysis of extracts of various cell lines, using Ceruloplasmin Antibody (STJ29972) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-CP antibody (366-572) (STJ29972)

SKU:
STJ29972

£169.50 - £449.50
Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ceruloplasmin (366-572) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CP
Gene ID: 1356
Uniprot ID: CERU_HUMAN
Immunogen Region: 366-572
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 366-572 of human Ceruloplasmin (NP_000087.1).
Immunogen Sequence: IRGKHVRHYYIAAEEIIWNY APSGIDIFTKENLTAPGSDS AVFFEQGTTRIGGSYKKLVY REYTDASFTNRKERGPEEEH LGILGPVIWAEVGDTIRVTF HNKGAYPLSIEPIGVRFNKN NEGTYYSPNYNPQSRSVPPS ASHVAPTETFTYEWTVPKEV GPTNADPVCLAKMYYSAVDP TKDIFTGLIGPMKICKKGSL HANGRQK
Tissue Specificity Expressed by the liver and secreted in plasma.
Function Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense.
Protein Name Ceruloplasmin
Ferroxidase
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-425410
Reactome: R-HSA-5619049
Reactome: R-HSA-5619060
Reactome: R-HSA-8957275
Reactome: R-HSA-917937
Cellular Localisation Secreted
Colocalizes With Gcp1 In Secretory Intracellular Compartments
Alternative Antibody Names Anti-Ceruloplasmin antibody
Anti-Ferroxidase antibody
Anti-CP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance