Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-DENR (1-198) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DENR |
Gene ID: |
8562 |
Uniprot ID: |
DENR_HUMAN |
Immunogen Region: |
1-198 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human DENR (NP_003668.2). |
Immunogen Sequence: |
MAADISESSGADCKGDPRNS AKLDADYPLRVLYCGVCSLP TEYCEYMPDVAKCRQWLEKN FPNEFAKLTVENSPKQEAGI SEGQGTAGEEEEKKKQKRGG RGQIKQKKKTVPQKVTIAKI PRAKKKYVTRVCGLATFEID LKEAQRFFAQKFSCGASVTG EDEIIIQGDFTDDIIDVIQE KWPEVDDDSIEDLGEVKK |
Tissue Specificity | Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney. |
Function | May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation.promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. |
Protein Name | Density-Regulated ProteinDrpProtein Drp1Smooth Muscle Cell-Associated Protein 3Smap-3 |
Alternative Antibody Names | Anti-Density-Regulated Protein antibodyAnti-Drp antibodyAnti-Protein Drp1 antibodyAnti-Smooth Muscle Cell-Associated Protein 3 antibodyAnti-Smap-3 antibodyAnti-DENR antibodyAnti-DRP1 antibodyAnti-H14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance