• Western blot analysis of extracts of various cell lines, using DENR antibody (STJ115654) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
  • Immunohistochemistry of paraffin-embedded rat heart using DENR antibody (STJ115654) at dilution of 1:150 (40x lens).

Anti-DENR antibody (1-198) (STJ115654)

SKU:
STJ115654

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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DENR (1-198) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DENR
Gene ID: 8562
Uniprot ID: DENR_HUMAN
Immunogen Region: 1-198
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human DENR (NP_003668.2).
Immunogen Sequence: MAADISESSGADCKGDPRNS AKLDADYPLRVLYCGVCSLP TEYCEYMPDVAKCRQWLEKN FPNEFAKLTVENSPKQEAGI SEGQGTAGEEEEKKKQKRGG RGQIKQKKKTVPQKVTIAKI PRAKKKYVTRVCGLATFEID LKEAQRFFAQKFSCGASVTG EDEIIIQGDFTDDIIDVIQE KWPEVDDDSIEDLGEVKK
Tissue Specificity Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney.
Function May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation.promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
Protein Name Density-Regulated Protein
Drp
Protein Drp1
Smooth Muscle Cell-Associated Protein 3
Smap-3
Alternative Antibody Names Anti-Density-Regulated Protein antibody
Anti-Drp antibody
Anti-Protein Drp1 antibody
Anti-Smooth Muscle Cell-Associated Protein 3 antibody
Anti-Smap-3 antibody
Anti-DENR antibody
Anti-DRP1 antibody
Anti-H14 antibody

Information sourced from Uniprot.org

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