| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DNAJC7 (230-380) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DNAJC7 |
| Gene ID: |
7266 |
| Uniprot ID: |
DNJC7_HUMAN |
| Immunogen Region: |
230-380 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 230-380 of human DNAJC7 (NP_003306.3). |
| Immunogen Sequence: |
VQFFVQALRMAPDHEKACIA CRNAKALKAKKEDGNKAFKE GNYKLAYELYTEALGIDPNN IKTNAKLYCNRGTVNSKLRK LDDAIEDCTNAVKLDDTYIK AYLRRAQCYMDTEQYEEAVR DYEKVYQTEKTKEHKQLLKN AQLELKKSKRK |
| Function | Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm. |
| Protein Name | Dnaj Homolog Subfamily C Member 7Tetratricopeptide Repeat Protein 2Tpr Repeat Protein 2 |
| Database Links | Reactome: R-HSA-3371453 |
| Cellular Localisation | CytoplasmNucleusCytoskeletonColocalizes With Nr1i3 To Microtubules |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily C Member 7 antibodyAnti-Tetratricopeptide Repeat Protein 2 antibodyAnti-Tpr Repeat Protein 2 antibodyAnti-DNAJC7 antibodyAnti-TPR2 antibodyAnti-TTC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
