Anti-EGFR (E746-A750 del) antibody

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Product name Anti-EGFR (E746-A750 del) antibody
Short Description Rabbit monoclonal against EGFR (E746-A750 del)
Description EGFR is a transmembrane tyrosine kinase that belongs to the HER/erbB protein family. Somatic mutations in the tyrosine kinase domain of EGFR are present in a subset of lung adenocarcinoma. Two types of mutations account for approximately 90% of mutant cases: a specific point mutation L858R which occurs in exon 21 and short in-frame deletions in exon 19. A common lesion in exon 19 is the deletion of E746-A750, although other variants can also occur.
Applications IHC
Dilution range 1:100-200
Immunogen Synthetic EGFR peptide with deletion of E746-A750
Storage Instruction Store at 2-8°C for up to 1 year
Note For Research Use Only (RUO).
Validated Application IHC
Host Rabbit
Clonality Monoclonal
Reactivity Human
Conjugation Unconjugated
Isotype IgG
Formulation Tissue culture supernatant with 0.2% BSA and 15mM sodium azide.
Swiss-Prot Key P00533
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