| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GDF2 (320-429) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GDF2 |
| Gene ID: |
2658 |
| Uniprot ID: |
GDF2_HUMAN |
| Immunogen Region: |
320-429 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 320-429 of human GDF2 (NP_057288.1). |
| Immunogen Sequence: |
SAGAGSHCQKTSLRVNFEDI GWDSWIIAPKEYEAYECKGG CFFPLADDVTPTKHAIVQTL VHLKFPTKVGKACCVPTKLS PISVLYKDDMGVPTLKYHYE GMSVAECGCR |
| Tissue Specificity | Detected in blood plasma (at protein level). |
| Post Translational Modifications | A reversible disulfide bond can be formed between the two subunits in the homodimer.this has no effect on GDF2 activity. |
| Function | Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. |
| Protein Name | Growth/Differentiation Factor 2Gdf-2Bone Morphogenetic Protein 9Bmp-9 |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Growth/Differentiation Factor 2 antibodyAnti-Gdf-2 antibodyAnti-Bone Morphogenetic Protein 9 antibodyAnti-Bmp-9 antibodyAnti-GDF2 antibodyAnti-BMP9 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
