Anti-GFAP antibody

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Product name Anti-GFAP antibody
Short Description Goat polyclonal against GFAP
Description Goat polyclonal antibody to GFAP. Glial fibrillary acidic protein is a major intermediate filament protein of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development.
Applications WB
Dilution range Western blot 1:500-1:5,000Immunofluorescence NDImmunohistochemistry (paraffin) NDImmunohistochemistry (frozen) ND
Specificity Detects endogenous levels of GFAP by Western blot.
Protein Name Glial fibrillary acidic protein (GFAP)
Immunogen Recombinant peptide derived from within residues 375 aa to the C-terminus of human GFAP produced in E. coli.
Immunogen Region C-Term
Storage Instruction Store at -20°, and avoid repeated freeze-thaw cycles.
Note For research use only (RUO).
Validated Application WB
Host Goat
Clonality Polyclonal
Reactivity Avian, Bovine, Canine, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Human, Mouse, Other, Porcine, Rabbit, Rat, Sheep, Simian
Conjugation Unconjugated
Concentration 3 mg/mL
Purification This antibody is epitope-affinity purified from goat antiserum.
Isotype IgG
Formulation PBS, 20% glycerol and 0.05% sodium azide.
Gene ID 2670
Gene Symbol GFAP
Molecular Weight 50 kDa
Database Links HGNC:4235
Alternative Names Glial fibrillary acidic protein (GFAP)
Function GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Post-translational Modifications Phosphorylated by PKN1.
Cellular Localization Cytoplasm. Associated with intermediate filaments.
Tissue Specificity Expressed in cells lacking fibronectin.
Swiss-Prot Key P14136_HUMAN
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