| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GPX7 (20-187) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GPX7 |
| Gene ID: |
2882 |
| Uniprot ID: |
GPX7_HUMAN |
| Immunogen Region: |
20-187 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 20-187 of human GPX7 (NP_056511.2). |
| Immunogen Sequence: |
QQEQDFYDFKAVNIRGKLVS LEKYRGSVSLVVNVASECGF TDQHYRALQQLQRDLGPHHF NVLAFPCNQFGQQEPDSNKE IESFARRTYSVSFPMFSKIA VTGTGAHPAFKYLAQTSGKE PTWNFWKYLVAPDGKVVGAW DPTVSVEEVRPQITALVRKL ILLKREDL |
| Tissue Specificity | Expressed in esophageal epithelial cells.expression is up-regulated after exposure to acidic bile acids. |
| Function | It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxygen species (ROS) and protects against oxidative DNA damage and double-strand breaks. |
| Protein Name | Glutathione Peroxidase 7Gpx-7Gshpx-7Cl683 |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Glutathione Peroxidase 7 antibodyAnti-Gpx-7 antibodyAnti-Gshpx-7 antibodyAnti-Cl683 antibodyAnti-GPX7 antibodyAnti-GPX6 antibodyAnti-UNQ469 antibodyAnti-PRO828 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
