• Western blot analysis of extracts of rat liver, using GRM1 antibody (STJ113703) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Immunofluorescence analysis of C6 cells using GRM1 rabbit polyclonal antibody (STJ113703) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Anti-GRM1 antibody (921-1010) (STJ113703)

SKU:
STJ113703

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Host: Rabbit
Applications: WB/IF
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GRM1 (921-1010) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GRM1
Gene ID: 2911
Uniprot ID: GRM1_HUMAN
Immunogen Region: 921-1010
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 921-1010 of human GRM1 (NP_001264993.1).
Immunogen Sequence: ETACNQTAVIKPLTKSYQGS GKSLTFSDTSTKTLYNVEEE EDAQPIRFSPPGSPSMVVHR RVPSAATTPPLPSHLTAEET PLFLAEPALP
Tissue Specificity Detected in brain.
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum. May function in the light response in the retina.
Protein Name Metabotropic Glutamate Receptor 1
Mglur1
Database Links Reactome: R-HSA-416476
Reactome: R-HSA-420499
Reactome: R-HSA-6794361
Reactome: R-HSA-9717207
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Metabotropic Glutamate Receptor 1 antibody
Anti-Mglur1 antibody
Anti-GRM1 antibody
Anti-GPRC1A antibody
Anti-MGLUR1 antibody

Information sourced from Uniprot.org

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