Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-GRM3 (23-170) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GRM3 |
Gene ID: |
2913 |
Uniprot ID: |
GRM3_HUMAN |
Immunogen Region: |
23-170 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 23-170 of human GRM3 (NP_000831.2). |
Immunogen Sequence: |
LGDHNFLRREIKIEGDLVLG GLFPINEKGTGTEECGRINE DRGIQRLEAMLFAIDEINKD DYLLPGVKLGVHILDTCSRD TYALEQSLEFVRASLTKVDE AEYMCPDGSYAIQENIPLLI AGVIGGSYSSVSIQVANLLR LFQIPQIS |
Tissue Specificity | Detected in brain cortex, thalamus, subthalamic nucleus, substantia nigra, hypothalamus, hippocampus, corpus callosum, caudate nucleus and amygdala. |
Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. |
Protein Name | Metabotropic Glutamate Receptor 3Mglur3 |
Database Links | Reactome: R-HSA-418594Reactome: R-HSA-420499 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Metabotropic Glutamate Receptor 3 antibodyAnti-Mglur3 antibodyAnti-GRM3 antibodyAnti-GPRC1C antibodyAnti-MGLUR3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance