• Western blot analysis of extracts of various cell lines, using GRM3 antibody (STJ23873) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-GRM3 antibody (23-170) (STJ23873)

SKU:
STJ23873

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GRM3 (23-170) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GRM3
Gene ID: 2913
Uniprot ID: GRM3_HUMAN
Immunogen Region: 23-170
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-170 of human GRM3 (NP_000831.2).
Immunogen Sequence: LGDHNFLRREIKIEGDLVLG GLFPINEKGTGTEECGRINE DRGIQRLEAMLFAIDEINKD DYLLPGVKLGVHILDTCSRD TYALEQSLEFVRASLTKVDE AEYMCPDGSYAIQENIPLLI AGVIGGSYSSVSIQVANLLR LFQIPQIS
Tissue Specificity Detected in brain cortex, thalamus, subthalamic nucleus, substantia nigra, hypothalamus, hippocampus, corpus callosum, caudate nucleus and amygdala.
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Protein Name Metabotropic Glutamate Receptor 3
Mglur3
Database Links Reactome: R-HSA-418594
Reactome: R-HSA-420499
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Metabotropic Glutamate Receptor 3 antibody
Anti-Mglur3 antibody
Anti-GRM3 antibody
Anti-GPRC1C antibody
Anti-MGLUR3 antibody

Information sourced from Uniprot.org

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