• Western blot analysis of extracts of mouse kidney, using HAO2 antibody (STJ117353) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-HAO2 antibody (1-351) (STJ117353)

SKU:
STJ117353

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-HAO2 (1-351) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HAO2
Gene ID: 51179
Uniprot ID: HAOX2_HUMAN
Immunogen Region: 1-351
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human HAO2 (NP_057611.1).
Immunogen Sequence: MSLVCLTDFQAHAREQLSKS TRDFIEGGADDSITRDDNIA AFKRIRLRPRYLRDVSEVDT RTTIQGEEISAPICIAPTGF HCLVWPDGEMSTARAAQAAG ICYITSTFASCSLEDIVIAA PEGLRWFQLYVHPDLQLNKQ LIQRVESLGFKALVITLDTP VCGNRRHDIRNQLRRNLTLT DLQSPKKGNAIPYFQMTPIS TSLCWNDLSWFQSITRLPII LKGILTKEDAELAVKHNVQ
Tissue Specificity Expressed in the liver and kidney.
Function Oxidase that catalyzes the oxidation of medium and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, to the correspondong 2-oxoacids. Its role in the oxidation of 2-hydroxy fatty acids may contribute to the general pathway of fatty acid alpha-oxidation (Probable). Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2. Is not active on glycolate, glyoxylate, L-lactate and 2-hydroxybutanoate.
Protein Name 2-Hydroxyacid Oxidase 2
Haox2
(S-2-Hydroxy-Acid Oxidase - Peroxisomal
Cell Growth-Inhibiting Gene 16 Protein
Long Chain Alpha-Hydroxy Acid Oxidase
Long-Chain L-2-Hydroxy Acid Oxidase
Database Links Reactome: R-HSA-390918
Reactome: R-HSA-9033241
Cellular Localisation Peroxisome
Alternative Antibody Names Anti-2-Hydroxyacid Oxidase 2 antibody
Anti-Haox2 antibody
Anti-(S-2-Hydroxy-Acid Oxidase - Peroxisomal antibody
Anti-Cell Growth-Inhibiting Gene 16 Protein antibody
Anti-Long Chain Alpha-Hydroxy Acid Oxidase antibody
Anti-Long-Chain L-2-Hydroxy Acid Oxidase antibody
Anti-HAO2 antibody
Anti-HAOX2 antibody
Anti-GIG16 antibody

Information sourced from Uniprot.org

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