| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HSD17B2 (100-387) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HSD17B2 |
| Gene ID: |
3294 |
| Uniprot ID: |
DHB2_HUMAN |
| Immunogen Region: |
100-387 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 100-387 of human HSD17B2 (NP_002144.1). |
| Immunogen Sequence: |
KYLDELGFTVFAGVLNENGP GAEELRRTCSPRLSVLQMDI TKPVQIKDAYSKVAAMLQDR GLWAVINNAGVLGFPTDGEL LLMTDYKQCMAVNFFGTVEV T |
| Tissue Specificity | Expressed in placenta. |
| Function | Catalyzes the NAD-dependent oxidation of the highly active 17beta-hydroxysteroids, such as estradiol (E2), testosterone (T), and dihydrotestosterone (DHT), to their less active forms and thus regulates the biological potency of these steroids. Oxidizes estradiol to estrone, testosterone to androstenedione, and dihydrotestosterone to 5alpha-androstan-3,17-dione. Also has 20-alpha-HSD activity. |
| Protein Name | 17-Beta-Hydroxysteroid Dehydrogenase Type 217-Beta-Hsd 220 Alpha-Hydroxysteroid Dehydrogenase20-Alpha-HsdE2dhEstradiol 17-Beta-Dehydrogenase 2Microsomal 17-Beta-Hydroxysteroid DehydrogenaseShort Chain Dehydrogenase/Reductase Family 9c Member 2Testosterone 17-Beta-Dehydrogenase |
| Database Links | Reactome: R-HSA-193144 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-17-Beta-Hydroxysteroid Dehydrogenase Type 2 antibodyAnti-17-Beta-Hsd 2 antibodyAnti-20 Alpha-Hydroxysteroid Dehydrogenase antibodyAnti-20-Alpha-Hsd antibodyAnti-E2dh antibodyAnti-Estradiol 17-Beta-Dehydrogenase 2 antibodyAnti-Microsomal 17-Beta-Hydroxysteroid Dehydrogenase antibodyAnti-Short Chain Dehydrogenase/Reductase Family 9c Member 2 antibodyAnti-Testosterone 17-Beta-Dehydrogenase antibodyAnti-HSD17B2 antibodyAnti-EDH17B2 antibodyAnti-SDR9C2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
