Anti-HSD17B4 Antibody

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Product name Anti-HSD17B4 Antibody
Short Description Rabbit polyclonal against HSD17B4
Description The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Peroxisomal multifunctional enzyme type 2
MFE-2
17-beta-hydroxysteroid dehydrogenase 4
17-beta-HSD 4
D-bifunctional protein
DBP
Multifunctional protein 2
MPF-2
Short chain dehydrogenase/reductase family 8C m
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 437-736 of human HSD17B4 (NP_000405.1).
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 3295
Gene Symbol HSD17B4
Molecular Weight 79.686 kDa
Database Links HGNC:5213
OMIM:233400
Reactome:R-HSA-193368
Alternative Names Peroxisomal multifunctional enzyme type 2
MFE-2
17-beta-hydroxysteroid dehydrogenase 4
17-beta-HSD 4
D-bifunctional protein
DBP
Multifunctional protein 2
MPF-2
Short chain dehydrogenase/reductase family 8C m
Function Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids, Catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids,
Cellular Localization Peroxisome
Tissue Specificity Present in many tissues with highest concentrations in liver, heart, prostate and testis
Swiss-Prot Key P51659
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