Anti-HTR1D Antibody

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Product name Anti-HTR1D Antibody
Short Description Rabbit polyclonal against HTR1D
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name 5-hydroxytryptamine receptor 1D
5-HT-1D
5-HT1D
Serotonin 1D alpha receptor
5-HT-1D-alpha
Serotonin receptor 1D
Immunogen A synthetic peptide corresponding to a sequence within amino acids 150-250 of human HTR1D (NP_000855.1).
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 3352
Gene Symbol HTR1D
Molecular Weight 41.907 kDa
Database Links HGNC:5289
OMIM:182133
Reactome:R-HSA-390666
Alternative Names 5-hydroxytryptamine receptor 1D
5-HT-1D
5-HT1D
Serotonin 1D alpha receptor
5-HT-1D-alpha
Serotonin receptor 1D
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin), Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase, Signaling inhibits adenylate cyclase activity, Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity, May also play a role in regulating the release of other neurotransmitters, May play a role in vasoconstriction,
Cellular Localization Cell membrane
Tissue Specificity Detected in brain neocortex and caudate nucleus (at protein level)
Swiss-Prot Key P28221
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