Anti-HTR1D antibody

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Product name Anti-HTR1D antibody
Short Description Rabbit polyclonal against HTR1D
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name 5-Hydroxytryptamine Receptor 1d
Serotonin 1d Alpha Receptor
Serotonin Receptor 1d
Immunogen A synthetic peptide corresponding to a sequence within amino acids 150-250 of human HTR1D (NP_000855. 1).
Storage Instruction Store at -20°C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 3352
Gene Symbol HTR1D
Molecular Weight Calculated: 41kDa. Observed: 50kDa
Alternative Names Anti-5-Hydroxytryptamine Receptor 1d antibody
Anti-5-Ht-1d antibody
Anti-5-Ht1d antibody
Anti-Serotonin 1d Alpha Receptor antibody
Anti-5-Ht-1d-Alpha antibody
Anti-Serotonin Receptor 1d antibody
Anti-HTR1D HTR1DA HTRL antibody
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction.
Cellular Localization Cell Membrane
Multi-Pass Membrane Protein
Tissue Specificity Detected in brain neocortex and caudate nucleus (at protein level).
Swiss-Prot Key 5HT1D_HUMAN
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