| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-IFI44L (1-200) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IFI44L |
| Gene ID: |
10964 |
| Uniprot ID: |
IF44L_HUMAN |
| Immunogen Region: |
1-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human IFI44L (NP_006811.2). |
| Immunogen Sequence: |
MEVTTRLTWNDENHLRKLLG NVSLSLLYKSSVHGGSIEDM VERCSRQGCTITMAYIDYNM IVAFMLGNYINLHESSTEPN DSLWFSLQKKNDTTEIETLL LNTAPKIIDEQLVCRLSKTD IFIICRDNKIYLDKMITRNL KLRFYGHRQYLECEVFRVEG IKDNLDDIKRIIKAREHRNR LLADIRDYRPYADLVSEIRI |
| Function | Type I interferon-stimulated gene (ISG) that plays a critical role in antiviral and antibacterial activity. During bacterial infection, promotes macrophage differentiation and facilitates inflammatory cytokine secretion. Plays a role in the control of respiratory syncytial virus/RSV infection, reducing the ability of the virus to replicate. Exhibits a low antiviral activity against hepatitis C virus. Acts also as a feedback regulator of IFN responses by negatively regulating IKBKB and IKBKE kinase activities through interaction with FKBP5. |
| Protein Name | Interferon-Induced Protein 44-Like |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Interferon-Induced Protein 44-Like antibodyAnti-IFI44L antibodyAnti-C1orf29 antibodyAnti-GS3686 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
